Results 81 to 90 of about 2,211,033 (313)

Conceptualization of the three components of the study.

open access: yes, 2023
Conceptualization of the three components of the study.
J. P. Dinis Teixeira (15361198)   +19 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Culturally-Responsive Case Conceptualization

open access: yes, 2022
Psychotherapists are living in the era of accountability in which practitioners are increasingly expected to provide counseling and therapy services that are effective.
Sperry, Jon, Turner, Lindsay
core  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Career Counseling-Focused Case Conceptualization

open access: yes, 2021
Dr. Jon Sperry gives a two-day webinar, Career Counseling-Focused Case Conceptualization for the Career Development Association of ...
Sperry, Jon
core  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

NATIONAL AND CULTURAL PECULIARITIES OF THE LOVE CONCEPT IN THE PHRASEOLOGICAL PICTURE OF THE WORLD

open access: yesГуманитарные и юридические исследования, 2021
The article studies national and cultural features of the LOVE concept as represented in paremiological constructions and set expressions. Actualization and special emphasis on nucleus socio-cultural spaces in the key conceptualized notions in any ...
G. Marinina, M. Pisklova
doaj  

Case Conceptualization in Eight Steps

open access: yes, 2019
This session describes an easy-to-master, 8-step strategy for developing a concise, accurate, and compelling case conceptualization. It begins by defining the Sperry and Sperry (2012) case conceptualization model.
Sperry, Len, Sperry, Jon
core  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

MILITARY METAPHORS AS MEANS OF POLITICAL VALIDITY REPRESENTATION IN YULIA TYMOSHENKO'S IDIOSTYLE

open access: yesВестник Кемеровского государственного университета, 2013
The paper represents a research of metaphors as cognitive mechanisms. The specific character of military metaphors and their role in conceptualization of Ukraine’spolitical life in Yulia Tymoshenko’sidiostyleare considered.
K. A. Kovaleva
doaj  

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