Results 91 to 100 of about 1,966,627 (313)

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Trauma-Informed Case Conceptualization

, 2022
May 18, 2023 & June 8, 2023: Trauma-informed Case Conceptualization [Webinar].
Sperry, Jon
core  

The Coding Process and Its Challenges

Grounded Theory Review: An International Journal, 2010
Coding is the core process in classic grounded theory methodology. It is through coding that the conceptual abstraction of data and its reintegration as theory takes place.
Judith A. Holton, Ph.D.
doaj   +2 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Culturally-Responsive Case Conceptualization

, 2022
Psychotherapists are living in the era of accountability in which practitioners are increasingly expected to provide counseling and therapy services that are effective.
Sperry, Jon, Turner, Lindsay
core  

Review and Recognition of the Book “Political Modernity and Review” [PDF]

پژوهش‌نامۀ انتقادی متون و برنامه‌های علوم انسانی, 2018
The political modernity is a book about the secularism and secular values. The author believes that current problems of society have roots in dedifferentiation between public and private sphere state and civil society and individuals and citizens.
Seyed Ebrahim Sarparast Sadat
doaj  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Study Variables Conceptualization and Operationalization.

, 2016
Study Variables Conceptualization and Operationalization.
Sara Mesquita da Silva (2852231), Jacky Boivin (2852237), Sofia Gameiro (2852234)   +2 more
core   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Case Conceptualization in Eight Steps

, 2019
This session describes an easy-to-master, 8-step strategy for developing a concise, accurate, and compelling case conceptualization. It begins by defining the Sperry and Sperry (2012) case conceptualization model.
Sperry, Len, Sperry, Jon
core