Results 101 to 110 of about 2,211,033 (313)
This chapter provides instruction, examples, and steps on how to begin the creative production process. Focus will be on user centered design, conceptualization, and creation of documents that define the scope of your personal Web portfolio project ...
John DiMarco
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Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Restructuring and Re-culturing the Secondary Schooling Sector to Accommodate Multi-Grade Teaching and Learning [PDF]
E-Journal of Humanities, Arts and Social SciencesThis paper interrogates why grade repetition is allowed to be a normality in public secondary schools. The paper was motivated by diverse discourses, some of which regard grade repetition to be the product of the absence of restructuring and re-culturing
Ngwako Solomon Modiba
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Millennials as Organizational Citizens: Conceptualization and Measurement Development
, 2020 Millennials as Organizational Citizens: Conceptualization and Measurement ...
Shih Yung Chou
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FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Hybrid Actor: A New Phenomenon in the Field of Non-State Actors
Czech Journal of International Relations, 2009 This paper argues that the contemporary state of the conceptualization of the non-state actor is no longer sufficient in the context of recent developments of non-state actors, and calls for a reconceptualization.
Martin Janků, Petr Zelinka
doaj
Conceptual thinking for a conceptual project
АрхитектонThe authors continue to develop and delve deeper into their ideas on conceptual design. Previously we examined the role and significance of a conceptual design within the framework of the antinomy "singular-universal" or, more specifically, "project - science".
Gushchin Alexander N. +1 more
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Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
A holistic market conceptualization
, 2015 Mainstream marketing’s view on markets builds on neoclassical economics. By integrating mainstream marketing thinking with the emergent marketing literature that acknowledges a set of shortcomings related to the neoclassical-based market ...
Storbacka K., Pels J., MELE, CRISTINA
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