Results 101 to 110 of about 1,966,627 (313)

Systematicity in the Metaphorical Conceptualization of Knowledge based on Visual Perceptions in Ain al-Quzat Hamedani’s Tamhidat va Nameh-ha: A Cognitive Approach [PDF]

Matn/Pizhūhī-i Adabī
The aim of the present research is to explain the existence of systematicity in the metaphorical conceptualization of knowledge based on visual perceptions in Ain al-Quzat Hamedani’s Tamhidat va Nameh-ha.
Alireza Hajiannezhad, Mona Babaei
doaj   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Conceptualization of the placebo response.

, 2016
Conceptualization of the placebo response.
Olivier Grondin (2794132), Pascal-Henri Keller (2794126), Francois Gonon (2794129), François Tison (360889)   +3 more
core   +1 more source

A scoping review of emotional contagion research with human subjects: identifying common trends of previous research and potential areas for future research

Frontiers in Psychology
IntroductionEmotional contagion (EC) involves the automatic mimicry and synchronization of expressions, vocalizations, and movements, resulting in emotional alignment between individuals.
Barret Michalec, Chad E. Forbes, Kevin Pardon, Bella Ayala, Diego Guevara Beltran, Clarice Douille, Kaitlyn Felix, Samantha Gnall, Michael Hoenack, Brooke McKeever, Daniel Nguyen, Nicole Piemonte, Sarah Portle   +12 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Conceptual thinking for a conceptual project

Архитектон
The authors continue to develop and delve deeper into their ideas on conceptual design. Previously we examined the role and significance of a conceptual design within the framework of the antinomy "singular-universal" or, more specifically, "project - science".
Gushchin Alexander N., Divakova Marina N.   +1 more
openaire   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Conceptualization of grammatical facts

Polylinguality and Transcultural Practices, 2009
The article is devoted to problems of conceptualization of grammatical facts which are reflected national world outlook of Russian bearers. In the methods of teaching Russian as a foreign it is expediently introduce the lexical versatilities of universal
L S Kruchkova
doaj  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source