Enhancing immunotherapy efficacy of hepatocellular carcinoma by inhibiting the key antioxidant factor Nrf2. [PDF]
Mol Ther OncolZhu Y, Liu M, Kwok HF, Chen L.
europepmc +1 more source
Site‐Specific Protein Bioconjugation Through Cellular Incorporation of Noncanonical Amino Acids
Angewandte Chemie, EarlyView.Genetic code expansion (GCE) enables site‐specific installation of noncanonical amino acids containing bioorthogonal conjugation handles, allowing precise, homogeneous protein modification. This review examines the principles of orthogonal translation, surveys the chemistries available for chemoselective labeling, and highlights emerging multi‐site ...
Rahul Sarkar +2 more
wiley +1 more source
Public perception of medical detection dogs and other COVID-19 testing strategies. [PDF]
Front Public HealthZacharias K +4 more
europepmc +1 more source
Noncanonical Peloruside A Biosynthesis by an Uncultivated Verrucomicrobiota Symbiont
Angewandte Chemie, EarlyView.Noncanonical biochemistry of the peloruside PKS characterized in this work, comprising double bond generation by a noncanonical tridomain (blue), acetyl‐CoA recycling (orange), and proofreading systems (purple and yellow). The Z‐double bond is installed by TEB1 through O‐acetylation and acetate elimination. The acyl ligase PelB (AL, orange) selectively
Amy E. Fraley +11 more
wiley +1 more source
A Scoping Review: The Effect of Anthropogenic Noise on Animal Welfare in Zoological Settings. [PDF]
Vet Med SciKruse TN, Flint M.
europepmc +1 more source
Post‐Synthetic Zinc Modifications to Correct Speciation in Ti‐MWW Zeolites for Catalytic Oxidation
Angewandte Chemie, EarlyView.Post‐synthetic Zn modifications of Ti‐MWW zeolite catalysts exhibit improved catalytic properties in the selective oxidation reaction, namely the ammoximation reaction. The origin of the beneficial effect of Zn is related via an array of spectroscopic and microscopic techniques to the modification of extra‐framework TiO2 and TiOx clusters and the ...
Christoph J. Kaul +10 more
wiley +1 more source
Evidence for a Cu(II)‐Catalysed CuAAC Reaction: A Combined Experimental and Computational Study
Angewandte Chemie, EarlyView.A new mechanistic pathway for the CuAAC reaction has been found to operate under specific reaction conditions. The pathway is catalysed by Cu(II) through a self‐assembled dinuclear Cu(II) complex that incorporates the triazole product. Computational analysis and assessment of generality are reported.
Matthew J. Andrews +12 more
wiley +1 more source
Editorial: Microbial community dynamics in agroecosystems: from disease suppression to soil health. [PDF]
Front MicrobiolShen M, Li J, He J, Gao L.
europepmc +1 more source