Results 1 to 10 of about 169,378 (259)

Understanding the human antibody repertoire

open access: yesMAbs, 2020
The origins of the various elements in the human antibody repertoire have been and still are subject to considerable uncertainty. Uncertainty in respect of whether the various elements have always served a specific defense function or whether they were ...
A. Rees
exaly   +2 more sources

Identification of HPV16 E1 and E2-specific T cells in the oropharyngeal cancer tumor microenvironment

open access: yesJournal for ImmunoTherapy of Cancer, 2023
Background High-risk human papillomavirus (HPV) is a primary cause of an increasing number of oropharyngeal squamous cell carcinomas (OPSCCs). The viral etiology of these cancers provides the opportunity for antigen-directed therapies that are restricted
Christine McInnis   +12 more
doaj   +1 more source

Not a First Language but One Repertoire: Translanguaging as a Decolonizing Project

open access: yesRELC Journal : A Journal of Language Teaching and Research in Southeast Asia, 2022
Translanguaging has opened up spaces to recognize the dynamic multilingualism of students in classrooms taught in dominant languages, and problematized concepts such as ‘additive bilingualism’.
Li Wei, Ofelia García
semanticscholar   +1 more source

TRUST4: immune repertoire reconstruction from bulk and single-cell RNA-seq data

open access: yesNature Methods, 2021
We introduce the TRUST4 open-source algorithm for reconstruction of immune receptor repertoires in αβ/γδ T cells and B cells from RNA-sequencing (RNA-seq) data.
Li Song   +5 more
semanticscholar   +1 more source

Idiotope-Driven T-Cell/B-Cell Collaboration-Based T-Cell Epitope Prediction Using B-Cell Receptor Repertoire Sequences in Infectious Diseases

open access: yesViruses, 2023
T-cell recognition of antigen epitopes is a crucial step for the induction of adaptive immune responses, and the identification of such T-cell epitopes is, therefore, important for understanding diverse immune responses and controlling T-cell immunity. A
Yukio Nakamura   +4 more
doaj   +1 more source

A cell atlas of human thymic development defines T cell repertoire formation

open access: yesScience, 2020
Thymus development, cell by cell The human thymus is the organ responsible for the maturation of many types of T cells, which are immune cells that protect us from infection.
Jong-Eun Park   +41 more
semanticscholar   +1 more source

The Current State of Bashkir Song Folklore: A Case Study of 21st-Century Expeditional Materials

open access: yesOriental Studies, 2021
Introduction. At present, people’s interest in the historical and ethnocultural heritage has increased, and the desire to preserve traditional values for future generations has grown stronger.
Aigul M. Khakimyanova
doaj   +1 more source

Longitudinal analysis reveals age-related changes in the T cell receptor repertoire of human T cell subsets

open access: yesJournal of Clinical Investigation, 2022
A diverse T cell receptor (TCR) repertoire is essential for protection against a variety of pathogens, and TCR repertoire size is believed to decline with age.
Xiaoping Sun   +17 more
semanticscholar   +1 more source

Modern Hopfield Networks and Attention for Immune Repertoire Classification [PDF]

open access: yesbioRxiv, 2020
A central mechanism in machine learning is to identify, store, and recognize patterns. How to learn, access, and retrieve such patterns is crucial in Hopfield networks and the more recent transformer architectures. We show that the attention mechanism of
M. Widrich   +10 more
semanticscholar   +1 more source

The influences of microbial colonisation and germ-free status on the chicken TCRβ repertoire

open access: yesFrontiers in Immunology, 2023
Microbial colonisation is paramount to the normal development of the immune system, particularly at mucosal sites. However, the relationships between the microbiome and the adaptive immune repertoire have mostly been explored in rodents and humans. Here,
Stefan Dascalu   +14 more
doaj   +1 more source

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