Results 1 to 10 of about 360,824 (309)

Identification of HPV16 E1 and E2-specific T cells in the oropharyngeal cancer tumor microenvironment

Journal for ImmunoTherapy of Cancer, 2023
Background High-risk human papillomavirus (HPV) is a primary cause of an increasing number of oropharyngeal squamous cell carcinomas (OPSCCs). The viral etiology of these cancers provides the opportunity for antigen-directed therapies that are restricted
Christine McInnis, Lakshmi Srinivasan, Anthony J Coyle, Shilpa Bhatia, Glenn J Hanna, Ann Marie Egloff, Brinda Vijaykumar, Qiaomu Tian, Yanbo Sun, Del Leistritz-Edwards, Charles T Quinn, Ravi Uppaluri, Daniel C Pregibon   +12 more
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Idiotope-Driven T-Cell/B-Cell Collaboration-Based T-Cell Epitope Prediction Using B-Cell Receptor Repertoire Sequences in Infectious Diseases

Viruses, 2023
T-cell recognition of antigen epitopes is a crucial step for the induction of adaptive immune responses, and the identification of such T-cell epitopes is, therefore, important for understanding diverse immune responses and controlling T-cell immunity. A
Yukio Nakamura, Meng Ling Moi, Takashi Shiina, Tadasu Shin-I, Ryuji Suzuki   +4 more
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The Current State of Bashkir Song Folklore: A Case Study of 21st-Century Expeditional Materials

Oriental Studies, 2021
Introduction. At present, people’s interest in the historical and ethnocultural heritage has increased, and the desire to preserve traditional values for future generations has grown stronger.
Aigul M. Khakimyanova
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The influences of microbial colonisation and germ-free status on the chicken TCRβ repertoire

Frontiers in Immunology, 2023
Microbial colonisation is paramount to the normal development of the immune system, particularly at mucosal sites. However, the relationships between the microbiome and the adaptive immune repertoire have mostly been explored in rodents and humans. Here,
Stefan Dascalu, Stefan Dascalu, Stephen G. Preston, Stephen G. Preston, Robert J. Dixon, Patrik G. Flammer, Steven Fiddaman, Amy Boyd, Joshua E. Sealy, Jean-Remy Sadeyen, Bernd Kaspers, Philippe Velge, Munir Iqbal, Michael B. Bonsall, Adrian L. Smith   +14 more
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Different Somatic Hypermutation Levels among Antibody Subclasses Disclosed by a New Next-Generation Sequencing-Based Antibody Repertoire Analysis

Frontiers in Immunology, 2017
A diverse antibody repertoire is primarily generated by the rearrangement of V, D, and J genes and subsequent somatic hypermutation (SHM). Class-switch recombination (CSR) produces various isotypes and subclasses with different functional properties ...
Kazutaka Kitaura, Hiroshi Yamashita, Hitomi Ayabe, Tadasu Shini, Tadasu Shini, Takaji Matsutani, Ryuji Suzuki, Ryuji Suzuki   +7 more
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Preparation of Children for the Performance of Works by Foreign Composers in the Original Language in the Academic Vocal Class [PDF]

Музыкальное искусство и образование, 2019
The article reveals pedagogical views on the works of foreign composers as a subject of training in the class of academic vocal in children’s music schools and art schools. The characteristic of representation in general educational programs of
Elena V. Nikolaeva, Alisa E. Kalina
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Sociocultural Functions of Choral Art in Subcarpathian Ruthenia in the 1920s–1930s

Культура і мистецтво у сучасному світі, 2023
The aim of the article is to identify the institutionalisation level of the musical culture of Subcarpathian Ruthenia during the interwar period, to reveal the sociocultural functions of choral music in the region, and to determine the index of society ...
Тетяна Росул
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Repertoire Construction for Critical Cross-Cultural Literacy of English Majors: Based on the Research Paradigm of Systemic Functional Linguistics

Frontiers in Psychology, 2022
The ambiguous development trend of cultural globalization brings both opportunities and challenges to China’s cultural development. English major in colleges and universities, a discipline of cross-cultural education, should look at the cultural ...
Ran Zhao, Danyun Lu
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Deep sequencing of the T cell receptor visualizes reconstitution of T cell immunity in mogamulizumab-treated adult T cell leukemia

OncoImmunology, 2018
Although the anti-CCR4 antibody mogamulizumab (moga) shows striking antitumor activity against adult T cell leukemia (ATL), it can also cause fatal immunological pathology such as severe skin rash and graft-versus-host disease, which might be attributed ...
Takero Shindo, Kazutaka Kitaura, Hiroshi Ureshino, Kazuharu Kamachi, Masaharu Miyahara, Kazuko Doi, Tatsuro Watanabe, Eisaburo Sueoka, Tadasu Shin-I, Ryuji Suzuki, Shinya Kimura   +10 more
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T‐cell receptor repertoire analysis for the diagnosis and treatment of solid tumor: A methodology and clinical applications

Cancer Communications, 2020
T cells, which are involved in adaptive immunity, are essential in the elimination of tumor cells. Mature T cells can specifically recognize the antigen on the major histocompatibility complex (MHC) molecule through T‐cell receptors (TCR).
Na Li, Jiani Yuan, Wenjia Tian, Lin Meng, Yongyu Liu   +4 more
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