Results 11 to 20 of about 757,066 (352)

Evolutionary ecology of opsin gene sequence, expression and repertoire. [PDF]

open access: yes, 2017
Linking molecular evolution to biological function is a long-standing challenge in evolutionary biology. Some of the best examples of this involve opsins, the genes that encode the molecular basis of light reception.
Owens, Gregory L, Rennison, Diana J
core   +1 more source

Different B cell subpopulations show distinct patterns in their IgH repertoire metrics

open access: yeseLife, 2021
Several human B cell subpopulations are recognised in the peripheral blood, which play distinct roles in the humoral immune response. These cells undergo developmental and maturational changes involving VDJ recombination, somatic hypermutation and class ...
Marie Ghraichy   +5 more
doaj   +1 more source

Using step width to compare locomotor biomechanics between extinct, non-avian theropod dinosaurs and modern obligate bipeds [PDF]

open access: yes, 2017
How extinct, non-avian theropod dinosaurs locomoted is a subject of considerable interest, as is the manner in which it evolved on the line leading to birds. Fossil footprints provide the most direct evidence for answering these questions. In this study,
Barrett, R S   +10 more
core   +1 more source

Deep sequencing of the T cell receptor visualizes reconstitution of T cell immunity in mogamulizumab-treated adult T cell leukemia

open access: yesOncoImmunology, 2018
Although the anti-CCR4 antibody mogamulizumab (moga) shows striking antitumor activity against adult T cell leukemia (ATL), it can also cause fatal immunological pathology such as severe skin rash and graft-versus-host disease, which might be attributed ...
Takero Shindo   +10 more
doaj   +1 more source

Next-Generation Immune Repertoire Sequencing as a Clue to Elucidate the Landscape of Immune Modulation by Host–Gut Microbiome Interactions

open access: yesFrontiers in Immunology, 2018
The human immune system is a fine network consisted of the innumerable numbers of functional cells that balance the immunity and tolerance against various endogenous and environmental challenges.
Tatsuo Ichinohe   +8 more
doaj   +1 more source

Norwegian Military Music and Edvard Grieg – an approach

open access: yesStudia Musicologica Norvegica, 2018
Since both Edvard Grieg’s 175th birthday and Norwegian military music’s 200th anniversary are celebrated in 2018, a first look at compositions by Grieg for military music was in order. As one of Norway’s most popular and beloved composers, his works made
Ina Rupprecht
doaj   +1 more source

Exploring the impact of clonal definition on B-cell diversity: implications for the analysis of immune repertoires

open access: yesFrontiers in Immunology, 2023
The adaptive immune system has the extraordinary ability to produce a broad range of immunoglobulins that can bind a wide variety of antigens. During adaptive immune responses, activated B cells duplicate and undergo somatic hypermutation in their B-cell
Aurelien Pelissier   +6 more
doaj   +1 more source

The antibody loci of the domestic goat (Capra hircus) [PDF]

open access: yes, 2018
The domestic goat (Capra hircus) is an important ruminant species both as a source of antibody-based reagents for research and biomedical applications and as an economically important animal for agriculture, particularly for developing nations that ...
Bickhart, Derek M.   +4 more
core   +1 more source

Repertoire-dependent immunopathology [PDF]

open access: yesJournal of Autoimmunity, 2007
In humans, limited T-cell receptor repertoire and lymphopenia are associated with severe eosinophilic inflammatory disease. A model of lymphopenia and reduced T-cell repertoire was created; C57BL/6 Rag2-/- mice received limited (30,000) or large (2 million) numbers of CD4 T-cells.
Joshua, Milner   +4 more
openaire   +2 more sources

Intrathecal B-cell activation in LGI1 antibody encephalitis. [PDF]

open access: yes, 2020
ObjectiveTo study intrathecal B-cell activity in leucine-rich, glioma-inactivated 1 (LGI1) antibody encephalitis. In patients with LGI1 antibodies, the lack of CSF lymphocytosis or oligoclonal bands and serum-predominant LGI1 antibodies suggests a ...
Dandekar, Ravi   +13 more
core  

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