Results 21 to 30 of about 757,066 (352)
Evolution of T cell receptor beta loci in salmonids
Frontiers in Immunology, 2023 T-cell mediated immunity relies on a vast array of antigen specific T cell receptors (TR). Characterizing the structure of TR loci is essential to study the diversity and composition of T cell responses in vertebrate species.
Pierre Boudinot +6 more
doaj +1 more source
Distinct, developmental stage-specific activation mechanisms of trypanosome VSG genes [PDF]
, 1990 The metacyclic form of African trypanosomes is the first to express genes for the Variant Surface Glycoprotein (VSG) and it uses an unusually predictable subset of the VSG gene repertoire.
Barry, J D +3 more
core +1 more source
Frontiers in ImmunologyIntroductionHuman peripheral blood mononuclear cells (hPBMCs) are widely used in fundamental research and clinical applications as studying their responses to in vitro activation is an effective way to uncover functional alterations and disease ...
Aline Linder +3 more
doaj +1 more source
Human Vaccines & Immunotherapeutics, 2021 The Hepatitis B (HB) vaccine is efficacious in preventing hepatitis B virus infection. However, the association between antibody response to the HB vaccine and dynamic immune repertoire changes in different cell subsets remains unclear.
Miaoxian Zhao +8 more
doaj +1 more source
Good-enough principles for welfare [PDF]
, 1999 The aim of this article is to widen the grounds of the debate on the relationship between values, social change and welfare reform. In the public debate on welfare reform and the Third Way the significance of the welfare politics and campaigns of civil ...
Williams, F.
core +1 more source
David Martin: my teacher, or, a way of seeing [PDF]
, 2020 David Martin’s sociology of religion embodied an expansive vision of religion, one that encompassed the entirety of human and social experience: its political, national, economic, aesthetic, poetical and spiritual-religious orientations, and the ...
Leoussi, Athena S.
core +1 more source
Inferring processes underlying B-cell repertoire diversity
, 2015 We quantify the VDJ recombination and somatic hypermutation processes in human B-cells using probabilistic inference methods on high-throughput DNA sequence repertoires of human B-cell receptor heavy chains.
Aleksandra M. Walczak +10 more
core +1 more source
Extinction of gene expression in somatic cell hybrids. a reflection of important regulatory mechanisms? [PDF]
, 1993 Extinction in somatic cell hybrids is a multifactorial process that leads to loss of cell-type-specific gene expression. The underlying mechanisms are thought to mirror, at least in part, the repertoire of regulatory mechanisms controlling mammalian cell
Boshart, Michael +2 more
core +1 more source
Analyzing Immunoglobulin Repertoires [PDF]
Frontiers in Immunology, 2018 Somatic assembly of T cell receptor and B cell receptor (BCR) genes produces a vast diversity of lymphocyte antigen recognition capacity. The advent of efficient high-throughput sequencing of lymphocyte antigen receptor genes has recently generated unprecedented opportunities for exploration of adaptive immune responses.
Chaudhary, Neha, Wesemann, Duane
openaire +4 more sources
Structurally Mapping Antibody Repertoires [PDF]
Frontiers in Immunology, 2018 Every human possesses millions of distinct antibodies. It is now possible to analyze this diversity via next-generation sequencing of immunoglobulin genes (Ig-seq). This technique produces large volume sequence snapshots of B-cell receptors that are indicative of the antibody repertoire. In this paper, we enrich these large-scale sequence datasets with
Konrad Krawczyk +16 more
openaire +3 more sources