Results 41 to 50 of about 360,824 (309)

Perturbations in the T cell receptor β repertoire during malaria infection in children: A preliminary study

Frontiers in Immunology, 2022
The changes occurring in the T cell repertoire during clinical malaria infection in children remain unknown. In this study, we undertook the first detailed comparative study of the T cell repertoire in African children with and without clinical malaria ...
Augustina Frimpong, Augustina Frimpong, Augustina Frimpong, Michael Fokuo Ofori, Michael Fokuo Ofori, Abdoelnaser M. Degoot, Kwadwo Asamoah Kusi, Kwadwo Asamoah Kusi, Buri Gershom, Jacob Quartey, Eric Kyei-Baafour, Nhi Nguyen, Wilfred Ndifon, Wilfred Ndifon   +13 more
doaj   +1 more source

Repertoire-dependent immunopathology [PDF]

Journal of Autoimmunity, 2007
In humans, limited T-cell receptor repertoire and lymphopenia are associated with severe eosinophilic inflammatory disease. A model of lymphopenia and reduced T-cell repertoire was created; C57BL/6 Rag2-/- mice received limited (30,000) or large (2 million) numbers of CD4 T-cells.
Joshua, Milner, Jerrold, Ward, Andrea, Keane-Myers, Booki, Min, William E, Paul   +4 more
openaire   +2 more sources

Repertoire Class: March 16, 1973 [PDF]

, 1973
This is the program for the Repertoire Class recital, held on March 16, 1973.
Division of Music, Repertoire Class
core  

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Deep exploration of the TCR CDR3β repertoire specific for viral CD4 T-cell epitopes inside the circulating T-cell repertoire

Frontiers in Immunology
IntroductionThis study provides an in-depth analysis of the diversity of the CD4 TCR CDR3β repertoire specific to influenza A (HA) and Epstein-Barr virus (EBNA) epitopes.MethodsEpitope-specific CD4 T cells from 13 healthy donors were enriched using a ...
Gautier Lhomme, Rémi Giraudet, Valéria Porcheddu, Evelyne Correia, Robert Olaso, Stephane Hua, Bernard Maillere   +6 more
doaj   +1 more source

Estimating the diversity, completeness, and cross-reactivity of the T cell repertoire

Frontiers in Immunology, 2013
In order to recognize and combat a diverse array of pathogens the immune system has a large repertoire of T cells having unique T cell receptors (TCRs) with only a few clones specific for any given antigen. We discuss how the number of different possible
Veronika eZarnitsyna, Brian eEvavold, Louie eSchoettle, Joseph eBlattman, Rustom eAntia   +4 more
doaj   +1 more source

Mapping what we know

Stridon, 2022
This article offers an outline of the literary translation flow from Turkish to Arabic between 1923 and 2005 based on a catalogue of translated literary works that were published in this period that was compiled for the purposes of this research.
Sare Rabia Öztürk
doaj   +1 more source

Repertoire Class: October 15, 1976 [PDF]

, 1976
This is the program for the Repertoire Class recital, held on October 15, 1976, in the Mabee Fine Arts Center Recital Hall.
Division of Music, Repertoire Class
core  

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

Clinical Features and T‐Cell Repertoire of Chronic Myeloid Leukemia Patients Who Attempt Discontinuation of Tyrosine Kinase Inhibitors: The ISAC‐TFR Study

Cancer Medicine
Background While tyrosine kinase inhibitor (TKI) discontinuation is an established therapeutic goal, up to 60% of patients relapse after the first attempt. The feasibility of a second or third attempt at TKI discontinuation remains uncertain.
Hiroshi Ureshino, Yukio Nakamura, Yemima Budirahardja, Iwao Nozawa, Keisuke Kidoguchi, Kazuharu Kamachi, Shinya Kimura   +6 more
doaj   +1 more source