Results 61 to 70 of about 360,824 (309)

Longitudinal analysis of the antibody repertoire of a Zika virus-infected patient revealed dynamic changes in antibody response

Emerging Microbes and Infections, 2020
The Zika virus (ZIKV) is a mosquito-borne flavivirus that causes neonatal abnormalities and other disorders. Antibodies to the ZIKV envelope (E) protein can block infection.
Xuefeng Niu, Qihong Yan, Zhipeng Yao, Fan Zhang, Linbing Qu, Chunlin Wang, Chengrui Wang, Hui Lei, Chaoming Chen, Renshan Liang, Jia Luo, Qian Wang, Lingzhai Zhao, Yudi Zhang, Kun Luo, Longyu Wang, Hongkai Wu, Tingting Liu, Pingchao Li, Zhiqiang Zheng, Yee Joo Tan, Liqiang Feng, Zhenhai Zhang, Jian Han, Fuchun Zhang, Ling Chen   +25 more
doaj   +1 more source

Repertoire Class: September 7, 1973 [PDF]

, 1973
This is the program for the Repertoire Class recital, held on September 7, 1973.
Division of Music, Repertoire Class
core  

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Repertoire Class: March 29, 1974 [PDF]

, 1974
This is the program for the Repertoire Class recital, held on March 29, 1974.
Division of Music, Repertoire Class
core  

In vitro generation of regulatory T cells: A challenging tool for studying immune aging in humans

FEBS Open Bio, EarlyView.
In vitro induction of human regulatory T cells using standard protocols generates suppressive, Foxp3‐expressing CD4+ T cells independently of TGF‐β supplementation and donor age. Regulatory T (Treg) cells play a key role in immune tolerance and homeostasis.
Lynn Muller, Jana Bleher, Birgit Weinberger, Lourdes Rocamora‐Reverte   +3 more
wiley   +1 more source

Human B-1 Cells and B-1 Cell Antibodies Change With Advancing Age

Frontiers in Immunology, 2019
Age-related deficits in the immune system have been associated with an increased incidence of infections, autoimmune diseases, and cancer. Human B cell populations change quantitatively and qualitatively in the elderly. However, the function of human B-1
Nely Rodriguez-Zhurbenko, Tam D. Quach, Thomas J. Hopkins, Thomas L. Rothstein, Thomas L. Rothstein, Ana M. Hernandez   +5 more
doaj   +1 more source

Repertoire Class: February 24, 1978 [PDF]

, 1978
This is the program for the Repertoire Class recital, held on February 24, 1978.
Division of Music, Repertoire Class
core  

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

On monotony of opera playbill and underlying economy

Musicologica Brunensia, 2018
The study explores modern opera theater repertoires and focuses on the strategy of opera offering. Statistics and data analysis reveal strong tendencies of monotony, sameness, and repetitiveness of repertoire across the biggest and most productive opera ...
Elena Khokhlova
doaj   +1 more source

Repertoire Class: March 10, 1966 [PDF]

, 1966
This is the program for the Repertoire Class recital, held on March 10, 1966.
Division of Music, Repertoire Class
core