Results 61 to 70 of about 757,066 (352)

Biomimetic Nanovaccine Integrating Dendritic Cell Exosomes with Tumor Cell Membranes for Sustained Prophylaxis Against Glioblastoma

Advanced Functional Materials, EarlyView.
We have developed DEX/GM, an all‐natural, personalizable hybrid vaccine designed by coating dendritic cell‐derived exosomes (DEX) onto tumor cell membranes (GM) for sustained prophylaxis against glioblastoma (GBM). ABSTRACT Glioblastoma (GBM), one of the most aggressive and lethal brain tumors, remains incurable with a poor clinical prognosis.
Shanshan Li, Dongya Zhang, Shiyu Wang, Changhe Pang, Meng Zheng, Bingyang Shi, Yan Zou   +6 more
wiley   +1 more source

Clinical Features and T‐Cell Repertoire of Chronic Myeloid Leukemia Patients Who Attempt Discontinuation of Tyrosine Kinase Inhibitors: The ISAC‐TFR Study

Cancer Medicine
Background While tyrosine kinase inhibitor (TKI) discontinuation is an established therapeutic goal, up to 60% of patients relapse after the first attempt. The feasibility of a second or third attempt at TKI discontinuation remains uncertain.
Hiroshi Ureshino, Yukio Nakamura, Yemima Budirahardja, Iwao Nozawa, Keisuke Kidoguchi, Kazuharu Kamachi, Shinya Kimura   +6 more
doaj   +1 more source

AIRR Community Standardized Representations for Annotated Immune Repertoires

Frontiers in Immunology, 2018
Increased interest in the immune system's involvement in pathophysiological phenomena coupled with decreased DNA sequencing costs have led to an explosion of antibody and T cell receptor sequencing data collectively termed “adaptive immune receptor ...
Jason Anthony Vander Heiden, Susanna Marquez, Nishanth Marthandan, Syed Ahmad Chan Bukhari, Christian E. Busse, Brian Corrie, Uri Hershberg, Uri Hershberg, Uri Hershberg, Steven H. Kleinstein, Steven H. Kleinstein, Frederick A. Matsen IV, Duncan K. Ralph, Aaron M. Rosenfeld, Chaim A. Schramm, The AIRR Community, Scott Christley, Uri Laserson   +17 more
doaj   +1 more source

Constructing the cultural repertoire in a natural disaster: The role of social media in the Thailand flood of 2011 [PDF]

, 2014
In 2011, Thailand witnessed its worst flooding catastrophe in half a century. In this study, we explored social media as a new and promising weapon to address the physical and morale challenges caused by the natural disaster.
Hackney, R, Kaewkitipong, L, Mao, M, Pan, SL, Ractham, P   +4 more
core   +1 more source

The Top Mass in Hadronic Collisions

, 2018
I discuss theoretical issues related to the top mass measurements in hadronic collisions.Comment: Contribution to the volume "From My Vast Repertoire - The Legacy of Guido Altarelli.
Nason, Paolo
core   +1 more source

Self‐Assembled Nanoclay Gel With Spheroid MSC‐Derived Exosome Mimetics to Integrate Demineralized Bone Matrix and Noggin‐Targeting miRNA for Synergistic Osteogenesis

Advanced Functional Materials, EarlyView.
We report a versatile nanoclay gel carrier platform that enhances the osteogenic efficacy of demineralized bone matrix (DBM) by integrating nanoclay‐based self‐assembly with cell‐derived exosome mimetics loaded with noggin‐targeting miR‐200c. This design amplifies BMP signaling, thereby promoting DBM‐mediated osteogenesis and offering a promising ...
Changlu Xu, Zhi Li, Minjee Kang, Ruoyu Sheng, Bing Han, Yiqing Chen, Tara Aghaloo, Min Lee   +7 more
wiley   +1 more source

Two operatic seasons of brothers Mingotti in Ljubljana

De Musica Disserenda, 2015
The brothers Angelo and Pietro Mingotti between 1736 and 1746 based in Graz organised during this period also two operatic seasons in Ljubljana, one in 1740 and the other in 1742. Two serious operas (Artaserse andRosmira) with comic intermezzi (Pimpinone
Metoda Kokole
doaj   +1 more source

Preparation of Children for the Performance of Works by Foreign Composers in the Original Language in the Academic Vocal Class [PDF]

Музыкальное искусство и образование, 2019
The article reveals pedagogical views on the works of foreign composers as a subject of training in the class of academic vocal in children’s music schools and art schools. The characteristic of representation in general educational programs of
Elena V. Nikolaeva, Alisa E. Kalina
doaj   +1 more source

Sound production in the Meagre, Argyrosomus regius (Asso, 1801): intraspecific variability associated with size, sex and context [PDF]

, 2020
Many fish taxa produce sound in voluntary and in disturbance contexts but information on the full acoustic repertoire is lacking for most species. Yet, this knowledge is critical to enable monitoring fish populations in nature through acoustic monitoring.
Amorim, Maria Clara P., Barata, Marisa, Candeias-Mendes, Ana, Fonseca, Paulo J., Pereira, Beatriz P., Pousão-Ferreira, Pedro, Vieira, Manuel   +6 more
core   +3 more sources

Enhanced Human Antigen‐Specific B Cell Responses Using In Vitro 3D Tonsil Cultures Containing Stromal Cells

Advanced Healthcare Materials, EarlyView.
We developed a fully human 3D tonsil cell culture system incorporating supportive stromal cells that better sustains and activates immune cells than conventional methods. The model generates stronger, more targeted antibody responses to viral antigens and vaccines, providing a physiologically relevant and entirely human platform for studying immune ...
Maaike V. J. Braham, Marlon de Gast, Liubov Babii, Sabine Kruijer, Theo M. Bestebroer, Mathilde Richard, Mathieu Claireaux, S. Marieke van Ham, Jelle de Wit, Cécile A. C. M. van Els, Anja ten Brinke, Marit J. van Gils   +11 more
wiley   +1 more source