Results 41 to 50 of about 393,346 (307)
Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
FEBS Open Bio, EarlyView.In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source
Resonancias, 2019 According to the New Grove, the coexistence of the terms concerto and concert allows us to distinguish between an instrumental genre characterized by the confrontation between one or several soloists and the rest of the ensemble, on the one hand, and an ...
Héctor Santos Conde
doaj +1 more source
Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen +8 more
wiley +1 more source
Le musicien ethnographe à l’épreuve de ses émotions
SociologiesThis article proposes a methodological reflection on how respondents can confront the researcher with his or her own emotions. For the purpose of my study I joined a punk music band, as a guitarist.
Sacha Thiébaud
doaj +1 more source
Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1
FEBS Open Bio, EarlyView.The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn +2 more
wiley +1 more source
Global Rather Than Vertical‐Selective Saccadic Abnormalities in Progressive Supranuclear Palsy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To test whether vertical saccades are preferentially affected in Progressive Supranuclear Palsy (PSP). Methods PSP patients (n = 24) were compared to age‐matched controls (n = 94) and two degenerative groups (Alzheimer's disease, n = 20; Lewy body disease, n = 50).
Duy Duan Nguyen +6 more
wiley +1 more source
, 1996 Program received, but no selections listedDigital audio of these performances is not yet available. You may submit a request for these recordings to be digitized and made available at this site within 10 work days at http://lib.asu.edu/music/services ...
core +1 more source
, 1995 Program received, but no selections listedDigital audio of these performances is not yet available. You may submit a request for these recordings to be digitized and made available at this site within 10 work days at http://lib.asu.edu/music/services ...
core +1 more source
Historically Informed Performance in Today’s Ukrainian Culture
Kyiv-Mohyla Humanities Journal, 2019 In the modern period in Ukrainian music culture early music and historically informed performance (HIP) has maintained the status of an “élite art.” The Early Music Department at theNational Music Academy of Ukraine (MNAU) was established more than two ...
Olena Zhukova
doaj