This study identifies C4 as a lead inhibitor of the Lpt system. Notably, C4 potentiates colistin activity by disrupting LPS transport and remodeling phospholipid homeostasis, revealing a functional interplay between the Lpt and Mla systems. These findings establish a mechanistic link between Lpt inhibition and membrane lipid remodeling, positioning Lpt–
Jianya Luo +6 more
wiley +1 more source
Health-promotion can sustain leisure participation among persons 80 years and older: results from the randomised controlled trial elderly persons in the risk zone. [PDF]
Østby RH +3 more
europepmc +1 more source
Polarization Dynamics in Ferroelectrics: Insights Enabled by Machine Learning Molecular Dynamics
Machine learning molecular dynamics is presented as a route to capture polarization switching, domain wall kinetics, topological polar textures, and polar mechanical coupling beyond the limits of conventional atomistic methods. This Perspective surveys recent progress and identifies key methodological directions, including long‐range electrostatics ...
Dongyu Bai +3 more
wiley +1 more source
Neighborhood Socioeconomic Status and Diverse Health-related Outcomes among American Indian and Alaska Native Peoples during the COVID-19 Pandemic. [PDF]
Amiri S +5 more
europepmc +1 more source
Under 660 nm visible light, Ru NCs efficiently photocatalyze nitrate‐to‐ammonium conversion and modulate oral nitrogen metabolism. They precisely perturb Veillonella parvula, block its key support to Porphyromonas gingivalis, and exert an “inhibiting without killing” antivirulence effect.
Jing Zhou +10 more
wiley +1 more source
Longitudinal regimes of arts and cultural engagement and frailty among older adults in the United States: a g-formula approach. [PDF]
Bu F +6 more
europepmc +1 more source
Our work bridges the gap between skyrmion discovery and material design by demonstrating how atomic‐scale control of exchange interactions enables tunable skyrmion phase transitions in centrosymmetric magnetic metals. ABSTRACT Magnetic skyrmions are topologically protected spin states that hold promise for shaping the future of electronics.
Dasuni N. Rathnaweera +9 more
wiley +1 more source
Fabrication of Composite Cathode for All‐Solid‐State Sodium Batteries
The design of composite cathodes for all‐solid‐state sodium batteries must address three critical challenges—interfacial side reactions, interfacial delamination, and highly tortuous transport pathways. This work outlines structural and interfacial strategies to optimize ion transport and mechanical stability, enabling durable, and high‐performance ...
Gaoming Sun +6 more
wiley +1 more source
Identifying the Initiation of Oshikatsu and Health-Promoting Activities Through Oshikatsu Among Older Adults: A Trajectory Equifinality Approach. [PDF]
Hosaka K, Tanaka T, Iijima K, Nihei M.
europepmc +1 more source

