Results 41 to 50 of about 39,156 (303)
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Ronnie James Dio: the man on the silver mountain
Ronald James Padovana was born 10 July 1942. In 1957 he began what became a fifty three-year career in music career. In 1960 he began singing under the name Ronnie Dio, and then Ronnie James Dio.
Joe Weber
doaj +1 more source
ELEMENTS OF MOVEMENT IN THE EDUCATIONAL CONCERT
The focal point of our study is the importance of introducing kinaesthetic elements in the educational concerts of the modern age. After a short historical introduction about the evolution of children’s concerts, we stopped in the present, describing the
Dalma TOADERE KOVÁCS
doaj +1 more source
Background This project was a continuation of my curatorial research work in developing new programming for large guitar ensemble and presenting it in innovative contexts.
Schaupp, Karin
core
But Is It Art? Female Performers in the Café-Concert [PDF]
The Café-Concert as an object of study has tended to attract the interest of art rather than theatre historians, despite the fact that it was the major form of popular entertainment in France during the nineteenth century.
Harris, Geraldine
core
Interpreting the effects of DNA polymerase variants at the structural level
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Curating and Creating Collective Artistic Experiences: The Role of the Choral Conductor
The commonly recognised image of a choral conductor is of a person who stands in front of a group of singers and uses a set of gestures to direct them in performance.
Róisín Blunnie, Orla Flanagan
doaj +1 more source
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Toward the concert and music tourism in Solo of Indonesia
Concerts are a fun attraction. This industry is growing along with the arrival of world bands/musicians to In-donesia and performances by domestic musicians. If packaged well, concerts become a music tourism attrac-tion.
I Dewa Gde Satrya
doaj +1 more source

