Results 41 to 50 of about 11,152 (268)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

This Is Not a Myeloproliferative Neoplasm…

open access: yes
Pediatric Blood &Cancer, EarlyView.
Stephanie Juané Kennedy
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Concession as the form of implementation of public-private partnership projects: the general description of accounting object

open access: yesВісник Житомирського державного технологічного університету: Серія: економіка, управління та адміністрування, 2019
The article explores the reasons for the emergence of the need for public-private partnership. The study found out that the most important reason was the existence of a gap between the public tasks that were set and the resources available in the state ...
V.V. Kovalchuk
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

THE POTENTIAL OF PUBLIC-PRIVATE PARTNERSHIP’S EMPLOYMENT IN URBAN PASSENGER TRANSPORT SPHERE IN OMSK

open access: yesВестник СибАДИ, 2017
Authors consider concept of public-private partnership, forms of its implementation. The Legislative acts, regulating the activities public-private partnerships, and features of Russian and foreign application experience are studied. It presents analyses
E. B. Lerman, S. A. Teslova
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

CONCESSION LEGISLATION OF THE RUSSIAN FEDERATION AND THE WTO: THE DOCTRINE AND PRACTICAL IMPLEMENTATION

open access: yesВестник Северо-Кавказского федерального университета, 2022
In thе article the concession legislation of the present from positions of scientists, and also it practice in the form of the Federal law from July, 21st, 2005 №115 «About concession agreements» is investigated.
Natalia V. Kuris, Vladimir N. Kuris
doaj  

The Concession Agreement as a Form of Involving Small Private Companies into the Effective Management of State Property

open access: yesУправленческие науки, 2017
Introduction, Purpose. The relevance of the study lies in the fact that the accumulated waste mining production, containing valuable components in industrial quantities, and can be subject to subsoil use, and, therefore, are objects of state ownership ...
O. Malikova, A. M. Maksimova
doaj   +1 more source

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