Results 61 to 70 of about 11,152 (268)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

CONCESSION USAGE EXPERIENCE IN NATIONAL ECONOMY OF RUSSIA

open access: yesНаука и техника, 2010
The paper considers stages concerning development of concession relations during a new economic policy. A structure of the concession organs and causes for closing down concession programs in the sovietRussiaare analyzed in the paper.
I. P. Zotova
doaj  

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Legal nature of the Concession Contract

open access: yesZbornik Radova Pravnog Fakulteta u Splitu, 2011
In this paper the authors analyse the legal nature of concession contract after the General Adiministrative Act came into force. Also, the concepts of concession and administrative contract in theory and in legislation are considered.
Marko Šikić, Frane Staničić
doaj  

USE OF THE CONCESSION MECHANISM FOR THE DEVELOPMENT OF DIFFICULT FOR ACCESS DEPOSITS OF MINERAL RESOURCES

open access: yesИзвестия высших учебных заведений: Геология и разведка, 2017
The problems of the concession development are considered, which is one of the forms of public-private partnership during developing difficult for access mineral deposits.
Z. M. Nazarova, Y. A. Leonidova
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

TRANSACTION COSTS OF THE CONCESSION AGREEMENT AS FORMS OF STATE-PRIVATE PARTNERSHIP

open access: yesВестник университета, 2017
The author of the article investigates the concession mechanism of public-private partnership, as well as transaction costs arising during the implementation of the concession project from the decision of the concluding member to conclude an agreement ...
A. Boldyrev
doaj  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Contract regulation of commercial concession (franchising): problems of civil law development

open access: yesRussian Journal of Economics and Law, 2014
Objective: to define the systems of legal regulation of commercial congcession (franchising) in the world practice. To reveal the features of commercial concession regulation in Russia.
N. A. Yushchenko, E. F. Gumerova
doaj  

Aspects on Practice of Concession in the Romanian Economy in Inter-War Period [PDF]

open access: yesOvidius University Annals: Economic Sciences Series, 2018
The restructuring and modernization of the Romanian economy and society in the interwarperiod imposed to governors, significant efforts, in order to accumulate the capital necessary toachieve the economic objectives.
Popa Florina
doaj  

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