Results 71 to 80 of about 300,037 (389)

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

THE POTENTIAL OF PUBLIC-PRIVATE PARTNERSHIP’S EMPLOYMENT IN URBAN PASSENGER TRANSPORT SPHERE IN OMSK

open access: yesВестник СибАДИ, 2017
Authors consider concept of public-private partnership, forms of its implementation. The Legislative acts, regulating the activities public-private partnerships, and features of Russian and foreign application experience are studied. It presents analyses
E. B. Lerman, S. A. Teslova
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

The Concession Agreement as a Form of Involving Small Private Companies into the Effective Management of State Property

open access: yesУправленческие науки, 2017
Introduction, Purpose. The relevance of the study lies in the fact that the accumulated waste mining production, containing valuable components in industrial quantities, and can be subject to subsoil use, and, therefore, are objects of state ownership ...
O. Malikova, A. M. Maksimova
doaj   +1 more source

Parasitism Revealed: On the Absence of Concession [PDF]

open access: yes, 2015
An examination of the role of ideologies from the past in shaping educational thought, action, policy and practice in the present. Takes the position that inequality is an expression of a fundamentally parasitic relationship forged during the 17th ...
Winfield, Ann G.
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

L’évolution des politiques de protection et l’intégration du secteur privé dans la conservation

open access: yesCaravelle, 2011
The model of concession was started in Colombia since 2005. This management strategy tries to advantage the territories’ economical development as well as the conservation of heritages.
Mara Sierra Jimenez
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Efficient Methods for Automated Multi-Issue Negotiation: Negotiating over a Two-Part Tariff

open access: yes, 2006
In this article, we consider the novel approach of a seller and customer negotiating bilaterally about a two-part tariff, using autonomous software agents.
Gerding, E. H.   +2 more
core  

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