Results 81 to 90 of about 300,037 (389)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
FINANCING OF RAILWAY INFRASTRUCTURE IN SLOVENIA [PDF]
In the paper we present a BOT (Build, Operate, Transfer) model of financing railway infrastructure development in the Republic of Slovenia. It is characteristic of this form of project financing that the host country or a local community grants a private
Dejan ROMIH, +2 more
core
Disaggregating U.S. Interests in International Law [PDF]
The Constitution is so central to American identity that any concession of external constitutional constraints may constitute a threat to national self-determination.
Spiro, Peter J.
core +1 more source
Practical Issues in the Application of Direct Metal Laser Sintering [PDF]
Direct Metal Laser Sintering (DMLS) was introduced to meet the objective of producing metal parts directly from CAD data. CRDM has accumulated six years of experience in applying this technique, mostly to prototyping parts for evaluation.
Bennett, G., Jacobson, D. M.
core +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Partnership of State and Business in Transcaucasia: History and Current Trends
The article aims to present generally the dynamics of political and economic systems on the territory of Transcaucasia in the period from the second millennium BC to the present.
E. A. Kuklina, V. S. Kuleshov
doaj +1 more source
The impact of private provision of public education : empirical evidence from Bogota's concession schools [PDF]
In 1999 the city of Bogota, Colombia launched the concession school program designed to broaden the coverage and quality of basic education. It consists of a contract between a group of private schools and the public educational system such that private ...
Barrera-Osorio, Felipe
core
PICALM::MLLT10 translocated leukemia
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Road infrastructure concession practice in Europe [PDF]
In a road infrastructure concession, a public authority grants specific rights to a private, or semi-public company to construct, overhaul, maintain, and operate infrastructure for a given period.
Bousquet, Franck, Fayard, Alain
core
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source

