Results 151 to 160 of about 77,030 (213)

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

[Analysis of the implementation of a Professional Pharmaceutical Service in Nutrition after 12 years operation]. [PDF]

Farm Comunitarios
Acuña Elvira N.
europepmc   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

XXVI Reunión Anual de la Sociedad Extremeña de Neurología. Comunicaciones Orales y Póster. [PDF]

Rev Neurol
europepmc   +1 more source

[Ischemic Priapism: evaluation in a third-level hospital in Mexico]. [PDF]

Rev Med Inst Mex Seguro Soc
Sánchez-Villaseñor G, Estrada-Vázquez E, Ramirez-Velázquez A, Vázquez-Sánchez SJ, González-Ojeda A, Gómez-Sierra JP, Fuentes-Orozco C.   +6 more
europepmc   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

[Management of pseudoaneurysm associated with endovascular treatments at third level]. [PDF]

Rev Med Inst Mex Seguro Soc
Páez-Sánchez MM, Calderón-Llamas MÁ, Nuño-Escobar C, Guerrero-Jauregui JÁ, Rodríguez-Ortega HA, Ramírez-Plascencia JI, Pedro Hugo PH, Olivas-Flores EM.   +7 more
europepmc   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

[Climate crisis and mental health: a scoping review eco-anxiety in latinamerican adults]. [PDF]

Rev Med Inst Mex Seguro Soc
Guarderas-Muñoz SJ, Carrera-Reyes C, Fuenmayor-González L.   +2 more
europepmc   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source