Results 151 to 160 of about 834,266 (237)

Conclusiones

open access: yesMateriales de Construccion, 1973
Equipo Editorial
doaj  

Conclusiones. Esto recién empieza...

open access: yesTelondefondo : Revista de Teoría y Crítica Teatral, 2018
UBACyT Los trabajadores del espectáculo en Buenos Aires: la especificidad laboral...
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

[A pioneering article that opens new lines of research into patient experience with clinical ultrasound]. [PDF]

open access: yesAten Primaria
Fernández-Guerrero IM   +2 more
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

[Sepsis in the Intermediate Respiratory Care Unit: Restrospective Study]. [PDF]

open access: yesOpen Respir Arch
Garcia Prieto F   +3 more
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Miscellaneæ Juris conclusiones controversæ

open access: yes
MISCELLANEÆ JURIS CONCLUSIONES CONTROVERSÆ Miscellaneæ Juris conclusiones controversæ ( - ) Title page ( - ) Dedication ( - ) Disputationis Inavgvralis Thesis I. [bis XX.] ( - ) XXI.
Tilenius, Nevelinus   +1 more
core  

Home - About - Disclaimer - Privacy