Results 141 to 150 of about 1,610,336 (282)

Whole-exome sequencing uncovers the genetic basis of hereditary concomitant exotropia in ten Chinese pedigrees

open access: yesBMC Medical Genomics
Purpose To explore possible pathogenic genes for concomitant exotropia using whole-exome sequencing. Methods In this study, 47 individuals from 10 concomitant exotropia (including intermittent exotropia and constant exotropia) pedigrees were enrolled ...
Wenhua Duan   +4 more
doaj   +1 more source

RESULTS OF CONCOMITANT PHOTON-NEUTRON THERAPY IN THE PALLIATIVE TREATMENT OF METASTATIC BRAIN TUMORS ACCORDING TO THE DATA OF THE CHELYABINSK REGIONAL CLINICAL ONCOLOGY DISPENSARY

open access: green, 2015
Г Г Бобкова   +5 more
openalex   +2 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Safety of Rimegepant in Patients Using Preventive Migraine Medications: A Subgroup Analysis of a Long-Term, Open-Label Study Conducted in the United States

open access: yesJournal of Pain Research
Gary Berman,1 Alexandra Thiry,2 Robert Croop3 1Clinical Research Institute, Minneapolis, MN, USA; 2Pfizer Inc., New York, NY, USA; 3Biohaven Pharmaceuticals, New Haven, CT, USACorrespondence: Gary Berman, Clinical Research Institute, 825 Nicollet Mall ...
Berman G, Thiry A, Croop R
doaj  

Primary hepatic neuroendocrine tumor with multiple intrahepatic metastases and concurrent hepatic angiomyolipoma: a case report and review of the literature

open access: yesJournal of Medical Case Reports
Background Primary hepatic neuroendocrine tumor is extremely rare, and hepatic angiomyolipoma is also a rare benign tumor of the liver with malignant biological behavior.
Yu-cen Shao   +3 more
doaj   +1 more source

Arsenic exposure-related hyperglycemia is linked to insulin resistance with concomitant reduction of skeletal muscle mass

open access: gold, 2020
Victor Mondal   +17 more
openalex   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Oblique impact: Projectile richochet, concomitant ejecta and momentum transfer [PDF]

open access: yes
Experimental studies of oblique impact indicate that projectile richochet occurs for trajectory angles less than 30 deg and that the richocheted projectile, accompanied by some target material, are ejected at velocities that are a large fraction of the ...
Gault, Donald E., Schultz, Peter H.
core   +1 more source

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