Results 151 to 160 of about 1,078,128 (318)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
*We only had information on urban or non-urban residency in 233 EAEC-positive with concomitant pathogens, 121 EAEC positive without concomitant pathogens, and 7639 EAEC-negative diarrhoeal episodes ^Only EAEC-positive with concomitant pathogens versus ...
Marit Gudrun Husby (18404414) +8 more
core +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Dharmakirti's Theory of Concomitance-Causality and Concomitance
JOURNAL OF INDIAN AND BUDDHIST STUDIES (INDOGAKU BUKKYOGAKU KENKYU), 1983 openaire +2 more sources
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Efficacy of fremanezumab in patients with chronic migraine and concomitant depression
Background. Migraine is a common chronic disorder that ranks third in the disability-adjusted life years among nervous system disorders. It is well known that migraine is strongly associated with the depression/anxiety disorders; there is overwhelming ...
A.Y. Timokhovich +2 more
core +1 more source
Concomitant Primary Cerebral Lymphoma and Meningioma
Iranian Journal of Neurosurgery, 2019 Background and Aim: Primary central nervous system lymphoma (PCNSL) is a rare cancer confined to the brain, spinal cord, leptomeninges and eyes. The origin of this type of lymphoma is often type B lymphocytes, and because the central nervous system (CNS)
Ehsan Mohammadhosseini +4 more
doaj
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Concomitant treatment for limbs undergoing FDO or TDO.
Concomitant treatment for limbs undergoing FDO or TDO.
Michael H. Schwartz (3310614) +3 more
core +1 more source