Results 121 to 130 of about 5,517,215 (329)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Miliary Tuberculosis due to Mycobacterium tuberculosis and Mycobacterium smegmatis associated with invasive aspergillosis in a renal transplant recipient

BMC Nephrology
Infections in renal transplant recipients (RTRs) carry great risk of morbidity-mortality, and the risk of graft loss. Concomitant infections, although common in immunosuppressed patients, should be highly suspected.
Andrade Sierra Jorge, Carvallo-Venegas Mauricio, Andrade-Ortega Antonio de Jesús, Andrade-Ortega Jorge, Cerrillos-Gutiérrez José Ignacio, Aguilar-Fletes Laura Elizabeth, Briseño-Hernández Andres Alejandro, Carrasco-Carrizosa Aldo   +7 more
doaj   +1 more source

Pulmonary nocardiosis and scrub typhus in an immunocompromised host

Journal of Global Infectious Diseases, 2018
Pulmonary infections are not uncommon in patients with an underlying immunocompromised condition. Unusual combination of microorganisms causing concomitant infections among these patients has also been reported. However, certain rare dual occurrences are
Isabella Princess, R Ebenezer, Nagarajan Ramakrishnan, S Nandini   +3 more
doaj   +1 more source

Clinical features and outcomes of COVID-19 patients with concomitant herpesvirus co-infection or reactivation: A systematic review

new microbes and new infections
Background Since the first case of COVID-19 was diagnosed in Wuhan, China in late 2019, concomitant infections with Herpesviridae were documented that were presented from simple skin manifestations to severe life-threatening conditions that may lead to ...
Shiny Talukder, Paroma Deb, M. Parveen, K. Zannat, A. Bhuiyan, M. Yeasmin, M. A. Molla, K. Saif-Ur-Rahman   +7 more
semanticscholar   +1 more source

Adult Hepatoblastoma and Concomitant Hepatitis B Infection

ACG Case Reports Journal
ABSTRACT We report a case of hepatoblastoma in a 26-year-old man with a background of type 2 diabetes mellitus and untreated hepatitis B, initially presenting with hematemesis and a recent diagnosis of hepatocellular carcinoma on computed tomography scan from a different hospital and recent referral to hospice.
Alejandro, Nieto Dominguez, Sarah Elizabeth, Eichinger, Elza, Matrova, Anas, Almoghrabi   +3 more
openaire   +2 more sources

Concomitant immunity against superimposed homologous Echinostoma caproni infections in mice is mediated by interleuquin-25 [PDF]

BACKGROUND The Institute of Cancer Research (ICR) mouse-Echinostoma caproni model is used to study mechanisms generating resistance against intestinal helminths due to the development chronic primary infections with Th1 responses, and partial resistance ...
Toledo Navarro, Rafael, Conciancic, Paola, Fiallos Gonzalez, Emma Karelia, Muñoz-Antoli, Carla, Esteban Sanchis, Jose Guillermo   +4 more
core  

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Other title: Healthcare Associated Infections annual report; Other title: Report to the legislature concerning the status of the Healthcare Associated Infections Initiative

, 2013
Annual; Began with Oct. 1, 2008.; "An Act Concerning Hospital Acquired Infections."; At head of title: State of Connecticut.; Volume for Oct.
Healthcare Associated Infections Program (Conn.)
core  

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source