Results 91 to 100 of about 9,683 (272)
Inflation persistence during periods of structural change: an assessment using Greek data
The paper estimates inflation persistence in Greece from 1975 to 2003, a period of high variation in inflation and changes in policy regimes. Two empirical methodologies, univariate autoregressive (AR) modelling and second-generation random coefficient ...
Hondroyiannis, George, Lazaretou, Sophia
core
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Estimating Parameters in Autoregressive Models with Asymmetric Innovations [PDF]
Tiku et al (1999) considered the estimation in a regression model with autocorrelated error in which the underlying distribution be a shift-scaled Student’s t distribution, developed the modified maximum likelihood (MML) estimators of the parameters and ...
Guorui Bian, Wing-Keung Wong
core
More on Stochastic Comparisons and Dependence among Concomitants of Order Statistics
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +2 more sources
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Information and Divergence Measures. [PDF]
Karagrigoriou A, Makrides A.
europepmc +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Asymptotic normality of linear functions of concomitants of order statistics
Let \((X_ 1,Y_ 1),...,(X_ n,Y_ n)\) be independent and identically distributed random vectors. Denote by \(Y_{[i:n]}\) the Y-variate corresponding to the ith order statistic \(X_{i:n}\) of \(X_ 1,...,X_ n\). In this paper statistics of the form \[ T_ n=n^{- 1}\sum^{n}_{i=1}J(i/n)h(X_{i:n},Y_{[i:n]}) \] are considered.
openaire +2 more sources
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Behavioral and cognitive-affective features of stuttering in preschool-age children: Regression and exploratory cluster analyses. [PDF]
Millager RA, Dietrich MS, Jones RM.
europepmc +1 more source

