Results 71 to 80 of about 173,505,036 (252)
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
, 2017 In this paper, we study on Fisher information (FI) of the dependence parameter for bivariate Farlie-Gumbel-Morgenstern (FGM) copula model in progressive type II censored order statistics and their concomitants.
Yıldız, Tuğba, Hüdaverdi, Burcu
core +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Molecular Oncology, EarlyView.This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan +8 more
wiley +1 more source
Residual and Past Entropies of Concomitants from Lai And Xie Extensions of Case-II of Generalized Order Statistics and its Dual [PDF]
In this article, we consider a new extensions of Morgenstern family is Lai and Xie extensions and discuss their concomitants for case-II of generalized order statistics and case-II of dual generalized order statistics.
S. Diab, L. +3 more
core +1 more source
CHARACTERIZATION OF INDUCED ORDER STATISTICS FROM RAYLIEGH BIVARIATE DISTRIBUTION [PDF]
, 2014 In this paper, a new bivariate distribution, using the concept given by Mongestern (1956), has been derived from univariate Rayleigh distribution. This new bivariate Rayleigh distribution is then considered to obtain the Induced (concomitants) order ...
Sarita Singh
core +2 more sources
Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma
Molecular Oncology, EarlyView.Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara +10 more
wiley +1 more source
Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer
Molecular Oncology, EarlyView.New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau +9 more
wiley +1 more source
Fisher information in order statistics and their concomitants in bivariate censored samples
Concomitants of order statistics, Type II censoring, Recurrence relation, Bivariate normal distribution, Information plot, Ranked set samples,
H. Nagaraja, Z. Abo-Eleneen
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Concomitants of Dual Generalized Order Statistics from Farlie Gumbel Morgenstern Type Bivariate Inverse Rayleigh Distribution [PDF]
, 2015 Dual generalized order statistics constitute a unified model for descending order random variables, like reverse order statistics and lower record values.
Athar, Haseeb, Nayabuddin,
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