Results 91 to 100 of about 9,687 (274)

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

A Portofolio Balance Approach to Euro-Area Money Demand in a Time-Varying Environment [PDF]

open access: yes
As part of its monetary policy strategy, the European Central Bank has formulated a reference value for M3 growth. A pre-requisite for the use of a reference value for M3 growth is the existence of a stable demand function for that aggregate.
George Hondroyiannis   +3 more
core  

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

Application of a simple nonparametric conditional quantile function estimator in unemployment duration analysis [PDF]

open access: yes
The paper analyses the potential impact of stock market developments on lending behaviour from different perspectives. First we scrutinize the impact of stock market movements on the banks? and on the borrowers? balance sheets.
Wichert, Laura, Wilke, Ralf A.
core   +3 more sources

Asymptotic normality of linear functions of concomitants of order statistics

open access: yesMetrika, 1987
Let \((X_ 1,Y_ 1),...,(X_ n,Y_ n)\) be independent and identically distributed random vectors. Denote by \(Y_{[i:n]}\) the Y-variate corresponding to the ith order statistic \(X_{i:n}\) of \(X_ 1,...,X_ n\). In this paper statistics of the form \[ T_ n=n^{- 1}\sum^{n}_{i=1}J(i/n)h(X_{i:n},Y_{[i:n]}) \] are considered.
openaire   +2 more sources

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

open access: yesFEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca   +6 more
wiley   +1 more source

Information and Divergence Measures. [PDF]

open access: yesEntropy (Basel), 2023
Karagrigoriou A, Makrides A.
europepmc   +1 more source

Inflation persistence during periods of structural change: an assessment using Greek data

open access: yes, 2004
The paper estimates inflation persistence in Greece from 1975 to 2003, a period of high variation in inflation and changes in policy regimes. Two empirical methodologies, univariate autoregressive (AR) modelling and second-generation random coefficient ...
Hondroyiannis, George, Lazaretou, Sophia
core  

Residual and Past Entropies of Concomitants from Lai And Xie Extensions of Case-II of Generalized Order Statistics and its Dual [PDF]

open access: yes
In this article, we consider a new extensions of Morgenstern family is Lai and Xie extensions and discuss their concomitants for case-II of generalized order statistics and case-II of dual generalized order statistics.
Gamal, A.   +3 more
core   +2 more sources

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

open access: yesFEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart   +7 more
wiley   +1 more source

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