Results 91 to 100 of about 1,154 (253)

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Fisher Information of Dependence in Progressive Type II Censored Order Statistics and Their Concomitants

open access: yes, 2017
In this paper, we study on Fisher information (FI) of the dependence parameter for bivariate Farlie-Gumbel-Morgenstern (FGM) copula model in progressive type II censored order statistics and their concomitants.
Yıldız, Tuğba, Hüdaverdi, Burcu
core  

Asymptotic normality of linear functions of concomitants of order statistics

open access: yesMetrika, 1987
Let \((X_ 1,Y_ 1),...,(X_ n,Y_ n)\) be independent and identically distributed random vectors. Denote by \(Y_{[i:n]}\) the Y-variate corresponding to the ith order statistic \(X_{i:n}\) of \(X_ 1,...,X_ n\). In this paper statistics of the form \[ T_ n=n^{- 1}\sum^{n}_{i=1}J(i/n)h(X_{i:n},Y_{[i:n]}) \] are considered.
openaire   +2 more sources

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Concomitants of Order Statistics from Marshall and Olkin's Bivariate Weibull Distribution

open access: yes, 2000
The probability density function (pdf) of the rth, 1 ≤ r ≤ n, concomitants of ordered statistics are derived for Marshall and Olkin's bivariate Weibull distribution and their moments are obtained. Also their means and variances are tabulated. AMS (2000)
Anjuman A. Begum, A. H. Khan
core   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

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