Results 41 to 50 of about 9,687 (274)

Concomitant of Order Statistics from New Bivariate Gompertz Distribution

Journal of Modern Applied Statistical Methods, 2020
For the new bivariate Gompertz distribution, the expression for probability density function (pdf) of rth order statistics and pdf of concomitant arising from rth order statistics are derived. The properties of concomitant arising from the corresponding order statistics are used to derive these results.
Sumit Kumar, M. J. S. Khan, Surinder Kumar   +2 more
openaire   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Correlation analysis of ordered symmetrically dependent observations and their concomitants of order statistics [PDF]

Canadian Journal of Statistics, 2006
AbstractGiven two jointly observed random vectors Y and Z of the same dimension, let Y be a reordered version of Y and Z the resulting vector of concomitants of order statistics. When X is a covariate of interest, also jointly observed with Y, the authors obtain the joint covariance structure of (X, y, Z) and the related correlation parameters ...
Viana, Marlos A. G., Lee, Hak-Myung
openaire   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Infant-mother attachment and the growth of externalizing problems across the primary-school years [PDF]

, 2011
Background:  Some contend that attachment insecurity increases risk for the development of externalizing behavior problems in children. Method:  Latent-growth curve analyses were applied to data on 1,364 children from the NICHD Study of Early Child ...
Achenbach, Ainsworth, Allison, Belsky, Belsky, Bentler, Curran, Curran, Erickson, Fearon, Kobak, Lamb, Lyons Ruth, Main, Matas, Moss, Muthén, NICHD Early Child Care Network., NICHD Early Child Care Research Network., Preacher, Renken, Rutter, Schafer, Van IJzendoorn, Vandell   +24 more
core   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Inflation Persistence during Periods of Structural Change: An Assessment Using Greek Data [PDF]

The paper estimates inflation persistence in Greece from 1975 to 2003, a period of high variation in inflation and changes in policy regimes. Three empirical methodologies, univariate autoregressive (AR) modelling, second-generation random coefficient ...
George Hondroyiannis, Sophia Lazaretou
core   +3 more sources

Domination of sample maxima and related extremal dependence measures

Dependence Modeling, 2018
For a given d-dimensional distribution function (df) H we introduce the class of dependence measures μ(H, Q) = −E{n H(Z1, . . . , Zd)}, where the random vector (Z1, . . . , Zd) has df Q which has the same marginal dfs as H. If both H and Q are max-stable
Hashorva Enkelejd
doaj   +1 more source