Results 41 to 50 of about 678,951 (271)

Clinical Characteristics and Prognostic Risk Factors for Pediatric B‐Cell Lymphoblastic Lymphoma: A Multicenter Retrospective Cohort Study for China Net Childhood Lymphoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐cell lymphoblastic lymphoma (B‐LBL) represents a rare variety of non‐Hodgkin lymphoma, with limited research on its biology, progression, and management. Methods A retrospective analysis was performed on the clinical characteristics of 256 patients aged ≤18 years who received treatment under the China Net Childhood Lymphoma (CNCL)‐
Zhijuan Liu, Jian Wang, Ling Jin, Yanlong Duan, Fu Li, Yueping Jia, Leping Zhang, Xiaojun Yuan, Wei Liu, Ying Liu, Ansheng Liu, Mincui Zheng, Yunpeng Dai, Lian Jiang, Lirong Sun, Xiaowen Zhai, Rong Liu, Chunju Zhou, Zifen Gao, Yonghong Zhang, Xiaomei Yang   +20 more
wiley   +1 more source

Comparative analysis of tax capacity in regions of Russia

Technological and Economic Development of Economy, 2016
Influence of tax policy of the state and its regions is vital for country’s economy; it is the major source of allocation of expenditure obligations of tax capacity on the sub-federal level.
Lyudmila Parfenova, Andrey Pugachev, Askoldas Podviezko   +2 more
doaj   +1 more source

Lagrangian concordance of Legendrian knots [PDF]

, 2010
In this article we define Lagrangian concordance of Legendrian knots, the analogue of smooth concordance of knots in the Legendrian category. In particular we study the relation of Lagrangian concordance under Legendrian isotopy.
Arnol’d, Arnol’d, Audin, Baptiste Chantraine, Bennequin, Bourgeois, Ekholm, Eliashberg, Etnyre, Ferrand, Geiges, Lalonde, Lees, Milnor, Viterbo   +14 more
core   +4 more sources

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Cortisol Responses to Naturally Occurring Psychosocial Stressors Across the Psychosis Spectrum: A Systematic Review and Meta-Analysis

Frontiers in Psychiatry, 2020
BackgroundIndividuals with established psychosis and those at high-risk for the disorder have been found to show abnormalities within the hypothalamic-pituitary-adrenal (HPA) axis, including elevations in basal and diurnal cortisol, but a blunted ...
Alexis E. Cullen, Sushma Rai, Meghna S. Vaghani, Valeria Mondelli, Valeria Mondelli, Philip McGuire, Philip McGuire   +6 more
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Impact of anemia and red cell indices on the diagnosis of pre-diabetes and diabetes in Indian adult population: Is there a cut-off guide for clinicians?

Indian Journal of Endocrinology and Metabolism, 2019
Background: It is well known that anemia and red cell turn over affects the HbA1c value. Iron deficiency anemia increases the HbA1c and haemolytic anemia lowers it. However, the cut-off of haemoglobin (Hb) or red-cell indices when the HbA1c value becomes
Subramanian Kannan, Chinthala Jaipalreddy, Vellaichamy Muthupandi Annapandian, Bangalore Venkatraman Murali Mohan, Sharat Damodar, Kranti Shreesh Khadilkar, Kumbenahalli Siddegowda Shivaprasad   +6 more
doaj   +1 more source

Seifert forms and concordance

, 2002
If a knot K has Seifert matrix V_K and has a prime power cyclic branched cover that is not a homology sphere, then there is an infinite family of non-concordant knots having Seifert matrix V_K.Comment: Shortened version containing the main examples ...
Casson, Charles Livingston, Cochran, Freedman, Freedman, Gilmer, Kim, Litherland, Matumoto, Rolfsen   +9 more
core   +1 more source

Genetic analysis of rare disorders: Bayesian estimation of twin concordance rates [PDF]

, 2012
Twin concordance rates provide insight into the possibility of a genetic background for a disease. These concordance rates are usually estimated within a frequentistic framework. Here we take a Bayesian approach.
Berg, S.M. van den, Hjelmborg, J.
core   +5 more sources