Results 61 to 70 of about 432,477 (298)

A Corpus-based Study of James Joyce’s A Portrait of the Artist as a Young Man

open access: yesCorporum, 2020
Exploring literary text(s) with corpus-based approaches is becoming popular and enlarging our understanding of a particular phenomenon in a text.
Muhammad Ajmal , Aisha Shoukat
doaj  

Concordance Between Watson for Oncology and Multidisciplinary Teams in Colorectal Cancer: Prognostic Implications and Predicting Concordance

open access: yesFrontiers in Oncology, 2020
BackgroundWatson for Oncology (WFO) is a cognitive computing system that provides clinical decision support. This study examined the concordance between the treatment recommendations for colorectal cancer (CRC) proposed by WFO and those recommended by ...
Chenchen Mao   +6 more
doaj   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Comparision of Direct Antibiotic Susceptibility Testing with Standard Testing in Blood Culture

open access: yesJournal of Pure and Applied Microbiology, 2018
To perform Direct Antibiotic Susceptibility Testing (DAST) on positive blood culture and compare with that of standard antibiotic susceptibility testing.
Rahila Yakoob, Gopalkrishna Bhat K.
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

open access: yesFEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez   +6 more
wiley   +1 more source

Concordance Percussion Ensemble, April 6, 1998 [PDF]

open access: yes, 1998
This is the concert program of the Concordance Percussion Ensemble performance on Monday, April 6, 1998 at 8:00 p.m., at the Concert Hall, 855 Commonwealth Avenue.
School of Music, Boston University
core   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

open access: yesFEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Rebuilding national unity through discourse in China: strategic narrative and concordance

open access: yesTIPA. Travaux interdisciplinaires sur la parole et le langage, 2017
The purpose of this article is to examine the discursive practices used by the Chinese political leadership in its attempts to rebuild national unity and avoid potential conflict in fostering concordance between three key actors, which are the Party, the
Laura-Anca Parepa
doaj   +1 more source

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