Results 41 to 50 of about 432,477 (298)

Contraceptive Concordance

open access: yesStudies in Family Planning
AbstractWe propose an indicator of contraceptive concordance that identifies the alignment between stated preferences for contraception and concurrent contraceptive behavior. Our indicator departs from traditional approaches to measurement in family planning that infer concordance to be the alignment between women's contraceptive (non‐)use and their ...
Sarah Vincent   +3 more
openaire   +4 more sources

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Comparative analysis of tax capacity in regions of Russia

open access: yesTechnological and Economic Development of Economy, 2016
Influence of tax policy of the state and its regions is vital for country’s economy; it is the major source of allocation of expenditure obligations of tax capacity on the sub-federal level.
Lyudmila Parfenova   +2 more
doaj   +1 more source

Cortisol Responses to Naturally Occurring Psychosocial Stressors Across the Psychosis Spectrum: A Systematic Review and Meta-Analysis

open access: yesFrontiers in Psychiatry, 2020
BackgroundIndividuals with established psychosis and those at high-risk for the disorder have been found to show abnormalities within the hypothalamic-pituitary-adrenal (HPA) axis, including elevations in basal and diurnal cortisol, but a blunted ...
Alexis E. Cullen   +6 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Concordance in action: case study of medication management

open access: yes, 2012
This article discusses a case study describing discontinuation symptoms relating to the abrupt withdrawal of the antidepressant venlafaxine. The article explores alternative explanations for the symptoms presented, and highlights the importance of ...
Roy, Dionne, Snowden, Austyn
core   +1 more source

Efficacy of concordance on the acquisition of polysemous words [PDF]

open access: yes, 2023
Acquisition of polysemous words is a prevalent and difficult process. This study aims to investigate the effectiveness of concordance on the acquisition of polysemous words, compared with the traditional teaching method. Participants were 127 Chinese EFL
Jingfen Jin
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Impact of anemia and red cell indices on the diagnosis of pre-diabetes and diabetes in Indian adult population: Is there a cut-off guide for clinicians?

open access: yesIndian Journal of Endocrinology and Metabolism, 2019
Background: It is well known that anemia and red cell turn over affects the HbA1c value. Iron deficiency anemia increases the HbA1c and haemolytic anemia lowers it. However, the cut-off of haemoglobin (Hb) or red-cell indices when the HbA1c value becomes
Subramanian Kannan   +6 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy