Results 61 to 70 of about 679,766 (271)

Comparisons of Concordance in Additive Models [PDF]

, 2012
In this note we compare bivariate additive models with respect to their Pearson correlation coecients, Kendall's concordance coecients, and Blomqvist medial correlation coefcients. The conditions that enable the comparisons involve variability stochastic
Bauerle, Blomqvist, Drouet Mari, Franco Pellerey, Khaledi, Kotz, Li, Marshall, Moshe Shaked, Müller, Nelsen, Salimeh Yasaei Sekeh, Saunders, Shaked, Youngren   +14 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

The concordance genus of knots

, 2004
In knot concordance three genera arise naturally, g(K), g_4(K), and g_c(K): these are the classical genus, the 4-ball genus, and the concordance genus, defined to be the minimum genus among all knots concordant to K. Clearly 0
Artin, Burde, Casson, Casson, Charles Livingston, Cochran, Conway, Donaldson, Fox, Fox, Freedman, Freedman, Gilmer, Gordon, Gordon, Kervaire, Kondo, Litherland, Matumoto, Milnor, Nakanishi, Rolfsen, Sakai, Schubert, Shibuya, Tristram, Witten   +26 more
core   +3 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Comparision of Direct Antibiotic Susceptibility Testing with Standard Testing in Blood Culture

Journal of Pure and Applied Microbiology, 2018
To perform Direct Antibiotic Susceptibility Testing (DAST) on positive blood culture and compare with that of standard antibiotic susceptibility testing.
Rahila Yakoob, Gopalkrishna Bhat K.
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Concordance Cosmology with Particle Creation

, 2013
A constant-rate creation of dark particles in the late-time FLRW spacetime provides a cosmological model in accordance with precise observational tests.
Carneiro, Saulo
core   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Concordance group and stable commutator length in braid groups

, 2014
We define a quasihomomorphism from braid groups to the concordance group of knots and examine its properties and consequences of its existence. In particular, we provide a relation between the stable four ball genus in the concordance group and the ...
Brandenbursky, Michael, Kędra, Jarek
core   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source