Results 31 to 40 of about 3,600 (262)

Effect of Stress–Strength Ratio and Fiber Length on Creep Property of Polypropylene Fiber-Reinforced Alkali-Activated Slag Concrete

open access: yesBuildings, 2022
Alkali-activated slag (AAS) is an environmentally friendly green cementitious material that can replace ordinary Portland cement (OPC) and has attracted extensive research by scholars all over the world.
Xianyu Zhou, Wenzhong Zheng, Yu Yan
doaj   +1 more source

Dose‐Dependent Reprogramming of Chromatin Accessibility by SOX4 Drives the Transcriptional Response to Iron Overload

open access: yesAdvanced Science, EarlyView.
This study demonstrates that iron overload triggers widespread chromatin compaction and transcriptional repression in human granulosa cells, recapitulating features of endometriosis. The epigenetic reprogramming is orchestrated by a TFEB‐SOX4‐SWI/SNF axis, with SOX4 acting as a central, dosage‐sensitive regulator.
Feifei Li   +15 more
wiley   +1 more source

Creep Characteristics Of Concrete Used In Long-Span Arch Bridge

open access: yesThe Baltic Journal of Road and Bridge Engineering, 2019
The reinforced concrete arch bridge with concrete-filled steel tubular stiffened skeleton is extensively used in the mountainous area of southwest China due to their long span and high stability. Beibanjiang Bridge located in Shanghai- Kunming high-speed
Yongbao Wang   +3 more
doaj   +1 more source

Cross‐Modal Denoising and Integration of Spatial Multi‐Omics Data with CANDIES

open access: yesAdvanced Science, EarlyView.
In this paper, we introduce CANDIES, which leverages a conditional diffusion model and contrastive learning to effectively denoise and integrate spatial multi‐omics data. We conduct extensive evaluations on diverse synthetic and real datasets, CANDIES shows superior performance on various downstream tasks, including denoising, spatial domain ...
Ye Liu   +5 more
wiley   +1 more source

Experimental and numerical modeling of creep in different types of concrete

open access: yesHeliyon, 2018
Creep in concrete, play a critical role in estimating losses in prestressed concrete structures, such as bridge girders, nuclear containment vessels, etc.
D. Harinadha Reddy, Ananth Ramaswamy
doaj   +1 more source

Stem Cell Differentiation Disperses Transcriptional Clusters via a Conserved Surface‐Condensate Trajectory

open access: yesAdvanced Science, EarlyView.
Stem cell differentiation follows a conserved surface condensate trajectory: H3K27ac super enhancers nucleate large RNA polymerase II clusters that grow and unfold before transcriptional activity disperses them. This work reveals how biophysical forces at enhancer surfaces dynamically build and dismantle stem cell transcription hubs, reshaping cell ...
Tim Klingberg   +18 more
wiley   +1 more source

Energy-based nonlinear damage creep model considering the influence of the concrete creep rate

open access: yesFrontiers in Materials
In order to study the influence of confining pressure on the deformation of concrete, triaxial compression and creep tests under different confining pressures are carried out using a combination of laboratory tests and theoretical analysis.
Lu Wang
doaj   +1 more source

Calibration and verification of creep parameters for concrete [PDF]

open access: yesMATEC Web of Conferences
Concrete is a material which undergoes slow increasing deformation while subjected to persistent mechanical stress. This phenomenon is known as creep. In concrete material, creep occurs at all stress levels.
Jindra Daniel, Hradil Petr, Kala Jiří
doaj   +1 more source

Temperature influence on creep of reinforced concrete

open access: yesRevista IBRACON de Estruturas e Materiais, 2020
: The creep of concrete promotes strains over time in structural members kept under sustained load. It causes the stress decrease on the concrete and the steel stress increase in reinforced concrete members. The moisture content and temperature influence
Edmilson Lira Madureira   +1 more
doaj   +1 more source

Stiffness‐Activated Stellate Cells Drive Pancreatic Cancer Liver Colonization via GMFG‐TNS4 Signaling

open access: yesAdvanced Science, EarlyView.
Fibrotic liver stiffness activates hepatic stellate cells through Piezo1‐dependent calcium influx and ER stress, promoting EV‐associated GMFG release. Delivered GMFG engages TNS4 in pancreatic cancer cells, triggering FAK/AKT signaling, adhesion, and fatty acid synthesis.
Biwen Zhu   +11 more
wiley   +1 more source

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