Results 131 to 140 of about 86,158 (275)

De Novo Multi‐Mechanism Antimicrobial Peptide Design via Multimodal Deep Learning

open access: yesAdvanced Science, EarlyView.
Current AI‐driven peptide discovery often overlooks complex structural data. This study presents M3‐CAD, a generative pipeline that leverages 3D voxel coloring and a massive database of over 12 000 peptides to capture nuanced physicochemical contexts.
Xiaojuan Li   +23 more
wiley   +1 more source

100 Türkçe ve Makedonca Sözcüğün Duygusal Değerlik, Somutluk ve Kullanım Sıklığı Düzeyinin Karşılaştırmalı İncelenmesi

open access: yesPsikoloji Çalışmaları
Sözcüklerin sıklık değerleri ve somutluk, imgelenebilirlik, duygusal değerlik veya uyarılmışlık gibi psikometrik özellikleri, başta deneysel ve bilişsel psikoloji araştırmaları olmak üzere psikolojinin birçok alanındaki çalışmalarda zihinsel süreçlerin ...
Simge Şişman Bal, Mevla Yahya
doaj   +1 more source

5. Paul Tillich

open access: yes, 1958
Paul Tillich (1886) left his native Germany because of the Nazis about the same time as Karl Earth, but Tillich came to the United States and became a faculty member of Union Theological Seminary, New York. He had spent World War I as a Lutheran chaplain
Bloom, Robert L.   +6 more
core  

The FOXC2‐LAMA4 Axis Orchestrates Vasculogenic Mimicry and Immunosuppressive Niche Formation to Drive Metastatic Cascade in Renal Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
Advanced clear cell renal cell carcinoma metastasis is driven by a FOXC2+ tumor subpopulation. These cells execute vasculogenic mimicry for dissemination and secrete LAMA4. LAMA4 engages macrophage ITGA6, activating the STAT6/GATA3 axis to polarize macrophages into a pro‐metastatic, immunosuppressive phenotype.
Jiaxi Yao   +11 more
wiley   +1 more source

β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto   +20 more
wiley   +1 more source

Mechanical Overloading‐Induced Nanomineral Crystal Perturbation from the Osteochondral Interface: A Potential Initiator of Osteoarthritis

open access: yesAdvanced Science, EarlyView.
Laser‐induced graphene (LIG) provides a scalable, laser‐direct‐written route to porous graphene architecture with tunable chemistry and defect density. Through heterojunction engineering, catalytic functionalization, and intrinsic self‐heating, LIG achieves highly sensitive and selective detection of NOX, NH3, H2, and humidity, supporting next ...
Nan Jiang   +8 more
wiley   +1 more source

From Tiles to Worksheet: Exploring Concreteness Fading in Learning Vector Addition

open access: yesEducation Sciences
Teaching vector addition seems challenging in secondary-level mathematics education. Vector addition requires both geometric and algebraic understandings, and the overreliance on abstract representations causes students difficulties in learning this ...
Yilang Zhao
doaj   +1 more source

Stabilization of Single Metal Atoms on Graphitic Carbon Nitride: Synthetic Strategies and Emerging Applications

open access: yesAdvanced Science, EarlyView.
This review highlights recent advancements in stabilizing single metal atoms on graphitic carbon nitride emphasizing innovative synthesis strategies and emerging applications in electrocatalysis, photocatalysis and organic transformations, along with key challenges and future perspective. Abstract Emerging as a new frontier in catalysis science, single‐
Wenyao Zhang   +6 more
wiley   +1 more source

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