Results 41 to 50 of about 15,372,779 (340)

Evolutionary interplay between viruses and R‐loops

FEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi, Zita Képes, Zoltán Szabó, Eszter Csoma, Lóránt Székvölgyi   +4 more
wiley   +1 more source

Assignment of Resources in Distributed Systems [PDF]

Journal of Systemics, Cybernetics and Informatics, 2018
In distributed processing systems it is often necessary to coordinate the allocation of shared resources that should be assigned in the processes in the modality of mutual exclusion; in such cases, the order in which the shared resources will be assigned
David L. La Red Martínez, Julio C. Acosta, Federico Agostini   +2 more
doaj  

Gender asymmetry in concurrent partnerships and HIV prevalence

Epidemics, 2017
The structure of the sexual network of a population plays an essential role in the transmission of HIV. Concurrent partnerships, i.e. partnerships that overlap in time, are important in determining this network structure.
Ka Yin Leung, Kimberly A. Powers, Mirjam Kretzschmar   +2 more
doaj   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

PROVING THE CORRECTNESS OF THE EXTENDED SERIAL GRAPH-VALIDATION QUEUE SCHEME IN THE CLIENT-SERVER SYSTEM

Barekeng
Numerous studies have been conducted to develop concurrency control schemes that can be applied to client-server systems, such as the Extended Serial Graph-Validation Queue (SG-VQ) scheme.
Fitra Nuvus Salsabila, Fahren Bukhari, Sri Nurdiati   +2 more
doaj   +1 more source

Reordering Transaction Execution to Boost High-Frequency Trading Applications

Data Science and Engineering, 2017
High-frequency trading (HFT) has always been welcomed because it benefits not only personal benefits but also the whole social welfare. While the recent advance of portfolio selection in HFT market enables to bring about more profit, it yields much ...
Ningnan Zhou, Xuan Zhou, Xiao Zhang, Xiaoyong Du, Shan Wang   +4 more
doaj   +1 more source

Token-Based Access Control

IEEE Access, 2020
Traditional centralized access control has some shortcomings in robustness, trustworthiness and circulation. Blockchains have the advantages of fault tolerance and trust.
Guohua Gan, E. Chen, Zhiyuan Zhou, Yan Zhu   +3 more
doaj   +1 more source

ParallelC-Assist: Productivity Accelerator Suite Based on Dynamic Instrumentation

IEEE Access, 2023
Software developers often face challenges in terms of quality and productivity to match competitive costs. The software industry seeks options to minimize this cost during different phases of software development and maintenance with improved ...
Nachiketa Chatterjee, Srijoni Majumdar, Partha Pratim Das, Amlan Chakrabarti   +3 more
doaj   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source