Results 121 to 130 of about 1,237,019 (300)

Explicit Model for Chiller Fault Diagnosis Based on Multi-objective Regression with Different Weights

open access: yesZhileng xuebao
Based on the cross-entropy loss function and stochastic gradient descent algorithm, a weight regression fault diagnosis model was established for seven common faults in a chiller.
Wu Kongrui   +4 more
doaj  

Shale oil technical advisory committee, minutes of the eleventh regular meeting

open access: yes, 2022
Includes charts.Unscanned drawing, contact the Library for more information. These minutes were recorded at the Technical Advisory Committee meetings and include agenda, budget, and technical reports about work performed at Anvil Points.A Technical ...

core  

Pyrazole‐Derived Antibacterial Compounds Effectively Treat Methicillin‐Resistant Staphylococcus Aureus Infections by Inhibiting Aspartate Transcarbamoylase

open access: yesAdvanced Science, EarlyView.
This study unveils a novel antibacterial mechanism against MRSA, in which the compound Py‐27 selectively targets and inhibits aspartate transcarbamoylase (ATCase), a key enzyme in pyrimidine synthesis. This inhibition disrupts DNA replication, induces oxidative damage, leading to potent bactericidal activity.
Xiaorong Yang   +11 more
wiley   +1 more source

Shale oil technical advisory committee, minutes of the second special meeting

open access: yes, 2022
Includes charts.These minutes were recorded at the Technical Advisory Committee meetings and include agenda, budget, and technical reports about work performed at Anvil Points.A Technical Advisory Committee was formed by Socony Mobil, ESSO Research and ...

core  

Probing Electrocatalyst Design for Product Selectivity in CO2 Reduction

open access: yesAdvanced Science, EarlyView.
Selective CO2 electroreduction is controlled by catalyst structure, dynamic surface reconstruction, adsorbate interactions, and reaction microenvironment. This review summarizes Cu‐ and non‐Cu‐based catalysts, single‐atom and molecular systems, degradation pathways, and operando/computational strategies for steering CO2RR toward hydrocarbons ...
Suvodeep Sen   +5 more
wiley   +1 more source

Demonstration of yield and operability retorting 3/4 to 1 1/2 inch oil shale at 500 lbs/(hr) (ft2) in retort no. 2

open access: yes, 2022
Technical memorandum no. 66-2.Includes charts.These technical memoranda pertain to work performed at Anvil Points.The United States Bureau of Mines facility at Anvil Points, near Rifle, Colorado, was reactivated starting in May 1964 and was operated ...

core  

Trafficking Deficiency of TMEM175 Variants in Parkinson's Disease Pathogenesis and the Prospects of Precision Medicine

open access: yesAdvanced Science, EarlyView.
This study identifies that the PD‐associated TMEM175‐L156P variant disrupts lysosomal ion channel trafficking by causing aberrant endoplasmic reticulum retention. A “chaperone–agonist” bifunctional small molecule restores TMEM175‐L156P lysosomal localization and channel function, thereby alleviating PD‐relevant cellular phenotypes and highlighting a ...
Ting Luo   +17 more
wiley   +1 more source

Cost study on underground mining of oil shale by the room and pillar method based upon research carried out during stage II

open access: yes, 2022
Technical memorandum no. 67 - 38.Unscanned map, contact the Library for more information. These Technical Memoranda have been prepared to provide rapid, on-the-spot reporting of research currently in progress at Anvil Points.The United States Bureau of ...

core  

Aberrant GRP78 Phase Transition Sustains Endothelial IRE1α Signaling and Drives Blood–Brain Barrier Failure in Cerebral Amyloid Angiopathy

open access: yesAdvanced Science, EarlyView.
Vascular Aβ40 corrupts GRP78 phase behavior in brain endothelial cells, sustaining IRE1α–TRAF2–JNK signaling and driving apoptosis, tight junction loss, and blood–brain barrier failure in cerebral amyloid angiopathy. Pharmacological IRE1α inhibition restores vascular integrity, reduces leakage, and improves functional outcomes, revealing a targetable ...
Honglin Zheng   +19 more
wiley   +1 more source

Mechanical model studies of the introduction and distribution of gas in a bed of oil shale (including commentary to technical film no. 66-4)

open access: yes, 2022
Technical memorandum no. 67-6.Includes charts.These technical memoranda pertain to work performed at Anvil Points.The United States Bureau of Mines facility at Anvil Points, near Rifle, Colorado, was reactivated starting in May 1964 and was operated ...

core  

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