Results 51 to 60 of about 509,143 (261)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Condition-Based Maintenance in Facilities Management

open access: yesComputing in Civil Engineering (2011), 2011
A facility management strategy requires that an organization’s major operational concerns are dealt with, such as: avoiding the risk of catastrophic failures, planning for asset maintenance and reducing the quantity of spare parts and associated inventory costs.
openaire   +2 more sources

Review of prognostic problem in condition-based maintenance [PDF]

open access: yes2009 European Control Conference (ECC), 2009
Prognostic is nowadays recognized as a key feature in maintenance strategies as it should allow avoiding inopportune maintenance spending. Real prognostic systems are however scarce in industry. That can be explained from different aspects, on of them being the difficulty of choosing an efficient technology: many approaches to support the prognostic ...
Otilia Elena Dragomir   +4 more
openaire   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

CONDITION BASED MAINTENANCE: STATUS AND FUTURE DIRECTIONS

open access: yesSouth African Journal of Industrial Engineering, 2012
<p>ENGLISH ABSTRACT: Research on condition-based maintenance (CBM) spans disciplines and introduces a wide range of concepts. On the basis of statistical analysis of the papers published in major maintenance-related journals, the development of the
S.A. Oke
doaj  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Maintenance optimization for rolling bearing based on delay time model

open access: yesInternational Journal for Simulation and Multidisciplinary Design Optimization
Rolling bearings are critical components in rotating machinery, directly influencing system reliability and performance. Bearing failures, driven by stochastic degradation processes, necessitate accurate reliability assessment and maintenance ...
Bui Minh-Hien   +4 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Cost-Optimal Maintenance Planning for Defects on Wind Turbine Blades

open access: yesEnergies, 2019
Due to the considerable increase in clean energy demand, there is a significant trend of increased wind turbine sizes, resulting in much higher loads on the blades.
Yi Yang, John Dalsgaard Sørensen
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

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