Results 91 to 100 of about 1,178,796 (218)
The discharge of effluents from shrimp farms into coastal lagoons can alter food availability, water quality, and pollutant load, potentially affecting the biological performance and safety of farmed bivalves. This study evaluated the influence of shrimp
Felipe de Jesús Reynaga-Franco +5 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
The Manila clam Ruditapes philippinarum is a commercially important bivalve worldwide, with China being the leading producer. While the reproductive biology of this species has been extensively studied in its native or long-established ranges, knowledge ...
Wei Guo +6 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Increasing atmospheric carbon dioxide (CO2) is driving global ocean acidification (OA). This process may threaten the persistence of bed-forming mussels by weakening the byssal system that anchors them to the seafloor. Here, blue mussels (Mytilus edulis)
Johanna Bürger +3 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
La extracción del mejillón Tagelus peruvianus representa una actividad económica complementaria de los pescadores artesanales, es una de las especies de mayor pesca y consumo ya que son una fuente importante de proteína, minerales y vitaminas esenciales ...
Cristian Fonseca Rodríguez +4 more
doaj
Parasites have the potential to impact aquaculture by degrading product quality, increasing mortality, and reducing fecundity. Previous research has identified a novel trematode parasite, Saccularina sp., infecting the gills of wild and cultured ...
Hailea F. H. Boggess +4 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source

