Results 151 to 160 of about 472,832 (312)

Adenylyl Cyclase 8 in Dorsal CA1 Neurons Prevents Depressive‐Like Behaviors by Maintaining Neuronal Excitability and Glutamatergic Neurotransmission Through TIP39‐PTH2R Signaling

Advanced Science, EarlyView.
Depression, a prevalent neuropsychiatric disorder with unclear pathogenesis, involves dysfunctional adenylyl cyclase 8 (Adcy8) as a key risk factor. Chronic stress selectively reduces Adcy8 expression in the dorsal CA1 (dCA1) neurons. Depletion of Adcy8 in dCA1 excitatory neurons induces depressive‐like behaviors by impairing neuronal excitability and ...
Zi‐Jie Liu, Jia‐Rui Bi, Zong‐Yan Yu, Meng Tian, Zhi‐Yue Chen, Ran Wei, Miao‐Miao Wang, Hai‐Wei Zha, Yu‐Qing Zhang, Hong‐Jing Wang, Bang‐You Qiang, Shuang‐Shuang Sun, Xiao‐Juan Zhu, Wen‐Bing Chen, Dong Sun   +14 more
wiley   +1 more source

Causal interventions in bond multi-dealer-to-client platforms. [PDF]

PLoS One
Marín Martínez P, Ardanza-Trevijano S, Sabio J.   +2 more
europepmc   +1 more source

Development of a genetically engineered mouse model of intraductal papillary mucinous neoplasm of the pancreas with the conditional expression of <i>GNAS^R201H</i>

, 2016
Toru Furukawa, Katsunobu Taki, Masaki Ohmuraya   +2 more
openalex   +2 more sources

Conditionally pathogenic genetic variants of a hematopoietic disease–suppressing enhancer

, 2021
Alexandra A. Soukup, Daniel R. Matson, Peng Liu, Kirby D. Johnson, Emery H. Bresnick   +4 more
openalex   +1 more source

Conditions and Conditionals [PDF]

, 1994
openaire   +2 more sources

Tubule‐Derived IFN‐α Promotes GSDMD‐Mediated Macrophage Pyroptosis to Drive Renal Inflammation and Fibrosis Through JAK2/STAT2 Activation

Advanced Science, EarlyView.
Mao and colleagues uncover a STAT2/IRF9‐dependent signaling axis through which tubular epithelial cell (TEC)‐derived IFN‐α induces gasdermin D (GSDMD)‐mediated pyroptosis in macrophages. This TEC‐macrophage feedback loop amplifies renal inflammation and fibrosis, providing mechanistic insight into the progression of chronic kidney disease and revealing
Yiping Xu, Yating Wang, Siming Jiang, Yi Li, Guanglan Li, Yuchu Liu, Siyuan Li, Yiming Zhou, Qinghua Liu, Yi Zhou, Wei Chen, Hongyu Li, Haiping Mao   +12 more
wiley   +1 more source

Population-Based analysis of conditional survival patterns and dynamic prognostic modeling in primary urinary tract lymphoma. [PDF]

Ann Hematol
Ke R, Nan C.
europepmc   +1 more source

Social Norms in Practice: The Boundaries and Conditionality of Income-Sharing Norms in Côte d’Ivoire

, 2017
Kristen McNeill
openalex   +1 more source

Ferroptosis‐Mediated Hippocampal Neuronal Loss Post‐mTBI: Chromatin Accessibility Profiling and Single‐Nucleus Transcriptomics

Advanced Science, EarlyView.
Hippocampal single ‐nucleus transcriptomes and chromatin accessibility after mild traumatic brain injury reveal dentate granule neuron vulnerability driven by ferroptosis. The c‐Jun–Tmsb4x–Slc2a2 axis modulates lipid peroxidation and iron dysregulation.
Manrui Li, Qiuyun Yang, Shengqiu Qu, Yang Chen, Yang Shen, Yang Xu, Xilong Lin, Yihan Sun, Ying Chen, Meili Lv, Lin Zhang, Zengqiang Yuan, Weibo Liang, Xiameng Chen   +13 more
wiley   +1 more source

On the virtues and limitations of Granger-causal brain connectivity estimate: Critical analysis using neural mass models. [PDF]

Netw Neurosci
Pelle S, Piermaria G, Magosso E, Ursino M.   +3 more
europepmc   +1 more source