Results 201 to 210 of about 221,779 (297)

Population-Based analysis of conditional survival patterns and dynamic prognostic modeling in primary urinary tract lymphoma. [PDF]

Ann Hematol
Ke R, Nan C.
europepmc   +1 more source

Liver Stiffness Characterization of OGTLKO Mouse Model of Progressive Liver Fibrosis

Journal of Ultrasound in Medicine, EarlyView.
Objectives O‐GlcNAcylation plays a key regulatory role in hepatic physiology, and its disruption leads to fibrosis in liver‐specific OGT knockout mice (OGTLKO), making this model valuable for studying advanced metabolic dysfunction‐associated steatohepatitis (MASH).
Gilles Renault, Lenin Chinchilla, Lourdes Massengo, Pierre Monbernard, Fadila Benhamed, Marion Regnier, Raphael Denis, Catherine Postic, Anthony Novell, Jean‐Luc Gennisson   +9 more
wiley   +1 more source

Refining the Liver Donor Risk Index With Machine Perfusion: A Bayesian Approach. [PDF]

Clin Transl Gastroenterol
Tanaka T, Sewell D.
europepmc   +1 more source

A Data‐Driven Redefinition of Early Relapse in Pediatric T Cell Acute Lymphoblastic Leukemia: Evidence for Progression of Disease 15 Months

Med Research, EarlyView.
Data‐driven redefinition of early relapse in pediatric T‐ALL using hazard modeling, cumulative incidence, and time‐dependent HR across 1533 patients in three independent cohorts identifies 15 months as the optimal threshold. By integrating temporal risk metrics and external validation, this study provides evidence for POD ≤ 15 months as a data‐driven ...
Na Zhang, Wenli Tang, Yali Shen, Yance Feng, Hui Shi, Binjun Xiong, Hua You   +6 more
wiley   +1 more source

Identity Matching and Stimulus Equivalence Learning Paradigms for Memory Rehabilitation of Explicit Memory Deficits: A Scoping Review. [PDF]

Perspect Behav Sci
Schedlowski J, Maes JHR, van Asselt RJ, Bertens D, Egger JIM, Kessels RPC.   +5 more
europepmc   +1 more source

Smart Integration of Structural Biology and Medicinal Chemistry to Unlock Target‐Driven Drug Discovery

Medicinal Research Reviews, EarlyView.
ABSTRACT To enhance drug discovery efforts, medicinal chemists should evaluate, filter, and utilize relevant structural information about target proteins. Acquiring and interpreting protein structures is crucial for elucidating ligand‐receptor interactions and addressing ADME‐related considerations, making it an essential aspect of medicinal chemistry.
Matteo Rossi Sebastiano, Giulia Apprato, Serena Francisco, Giuseppe Ermondi, Giulia Caron   +4 more
wiley   +1 more source

Mean‐Variance Payoff Applied to Stackelberg Games

Mathematical Methods in the Applied Sciences, EarlyView.
ABSTRACT We analyse a Stackelberg duopoly in which the leader faces uncertainty about the intercept demand, while the follower observes the realised demand and decides whether to enter the market after the uncertainty is resolved. The leader evaluates the uncertainty by maximising a mean‐variance utility function that captures its risk aversion.
João M. Silva, Margarida A. Brito, Alberto A. Pinto, Alberto A. Álvarez‐López   +3 more
wiley   +1 more source

Lipidomic profiles associated with treatment related hepatotoxicity in children with acute lymphoblastic leukemia. [PDF]

Support Care Cancer
Mason EJ, Schraw JM, Woodhouse JP, Gramatges MM, Williams KJ, Chen B, Harrell MB, Taylor OA, Scheurer ME, Lupo PJ, Rabin KR, Yi JS, Huynh V, Mittelman SD, Orgel E, Brown A.   +15 more
europepmc   +1 more source

Should We Consider Sacral Nerve Stimulation as a Treatment for Neurogenic Lower Urinary Tract Dysfunction? ICI‐RS 2025

Neurourology and Urodynamics, EarlyView.
ABSTRACT Aims To explore the boundary of clinical use of sacral nerve stimulation (SNS) in neurogenic lower urinary tract dysfunction (NLUTD), identifying barriers to approval and early‐impact research questions. Methods This review is derived from a proposal discussion at the International Consultation on Incontinence‐Research Society in Bristol in ...
Marcus J. Drake, Mathijs de Rijk, Stefania Musco, Jalesh Panicker, Michał Późniak, Nikita Bhatt, Brigitte Schurch   +6 more
wiley   +1 more source

Multi-objective Big Bang Big Crunch framework for reliable rice disease and variety classification with conditional calibration. [PDF]

PLoS One
Singh C, Singh A, Dhelim S.
europepmc   +1 more source