Results 91 to 100 of about 399,623 (235)

Probabilistic Computing via Gate‐Tunable Random Telegraph Noise

open access: yesAdvanced Science, EarlyView.
Intrinsic random telegraph noise in metal–oxide–semiconductor field‐effect transistors is harnessed to create gate‐tunable probabilistic bits. By modulating carrier‐trapping dynamics, the device produces stochastic binary outputs with a continuous bias‐to‐probability transfer.
Gyungwon Yun   +8 more
wiley   +1 more source

Prion‐Like Protein LENG8‐Mediated Nucleation Drives Stress Granule Assembly

open access: yesAdvanced Science, EarlyView.
LENG8 is a newly identified stress granule (SG) nucleator required for SG assembly. Following stress, nuclear LENG8 granules disassemble, allowing LENG8 to translocate into the cytoplasm and form independent nucleation foci. These foci fuse with canonical early G3BP1/TIA1 seeds via LENG8‐TIA1 binding to drive SG maturation.
Mingxing Zhang   +6 more
wiley   +1 more source

The impact of divorce laws on marriage-specific capital [PDF]

open access: yes
This paper considers how divorce law alters the incentives for couples to invest in their marriage, focusing on the impact of unilateral divorce laws on investments in new marriages.
Betsey Stevenson
core  

The Impact of Unilateral Divorce on Crime [PDF]

open access: yes
In this paper, we evaluate the impact of unilateral divorce on crime. First, using crime rates from the FBI’s Uniform Crime Report program for the period 1965-1998 and differences in the timing in the introduction of the reform, we find that unilateral ...
Giolito, Eugenio P.   +1 more
core   +2 more sources

Mutant KRAS‐m6A Epitranscriptome Axis Promotes Colorectal Cancer and is a Therapeutic Target

open access: yesAdvanced Science, EarlyView.
Mutant KRAS‐m6A axis promotes colorectal cancer (CRC) progression. Mutant KRAS stabilizes METTL3, leading to increased m6A‐modified BCL9L mRNA and translation of BCL9L protein. BCL9L in turn mediates TGF‐β secretion to induce differentiation of Treg and an immunosuppressive microenvironment.
Danyu Chen   +12 more
wiley   +1 more source

On the Causes and Consequences of Divorce [PDF]

open access: yes
In most Western economies, the flourishing of the Welfare State has coincided with a decline of the role of the family: divorce has been introduced, and the number of marriages has decreased.
Cinzia Ciardi   +2 more
core  

Glucocorticoid Receptor Signaling in Myeloid Cells Orchestrates Inflammation Resolution and Muscle Repair

open access: yesAdvanced Science, EarlyView.
Glucocorticoids (GC) are widely used to reduce inflammation. We show that the glucocorticoid receptor in myeloid cells regulates macrophage cell cycle and genome integrity during muscle regeneration. We demonstrate that dexamethasone administration during the early inflammatory phase delays muscle repair by increasing macrophage proliferation ...
Sirine Souali‐Crespo   +11 more
wiley   +1 more source

The topography of the divorce plateau [PDF]

open access: yes
The probability of divorce in the U.S. has remained constant for the last two decades at about 'half of all marriages.' While this estimate is well established, and marked differentials in divorced rates are well known, there are no reliable estimates of
Larry L. Bumpass, R. Kelly Raley
core  

Mapping Embryonic Mouse Lung Development Using Enhanced Spatial Transcriptomics

open access: yesAdvanced Science, EarlyView.
The mammalian lung contains ∼50 cell types arranged along the airway epithelium. Here, deterministic barcoding sequencing (DBiT‐seq) is optimized to nearly double transcript recovery, enabling highly sensitive spatial mapping of the embryonic mouse lung.
Pengfei Zhang   +5 more
wiley   +1 more source

Socioeconomic differentials in divorce risk by duration of marriage [PDF]

open access: yes
Using register-based data on Finnish first marriages that were intact at the end of 1990 (about 2.1 million marriage-years) and followed up for divorce in 1991-1993 (n = 21,204), this research explored the possibility that the effect of spouses ...
Marika Jalovaara
core  

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