Results 51 to 60 of about 399,623 (235)

The effect of divorce laws on divorce rates in Europe [PDF]

open access: yes
This paper analyzes a panel of 18 European countries spanning from 1950 to 2003 to examine the extent to which the legal reforms leading to “easier divorce” that took place during the second half of the 20th century have contributed to the increase in ...
Tarja K. Viitanen   +1 more
core  

Chimeric IL‐6/4R‐LL37 Engineered Macrophages Achieve Synchronized Inflammation Control and Antimicrobial Defence in Sepsis

open access: yesAdvanced Science, EarlyView.
Engineered macrophages programmed in situ by LNP‐delivered IL‐6/4 fusion and LL37 mRNAs simultaneously dampen cytokine storm, promote M2‐like repair, and enhance direct bacterial killing in sepsis. This combinatorial strategy restores T cell and macrophage function, lowers organ bacterial burden, and improves survival, highlighting a precision, host ...
Tianyang Jie   +10 more
wiley   +1 more source

Did Unilateral Divorce Laws Raise Divorce Rates? A Reconciliation and New Results [PDF]

open access: yes
Application of the Coase Theorem to marital bargaining suggests that shifting from a consent divorce regime to no-fault unilateral divorce laws should not affect divorce rates. Each iteration of the empirical literature examining the evolution of divorce
Justin Wolfers
core  

VlPAG/DRN Microglia Drive Neuropathic Pain‐Induced Depression via a Defined Neuroimmune Axis

open access: yesAdvanced Science, EarlyView.
Peripheral nerve injury (SNI) induces neuropathic pain, activates midbrain microglia, and triggers an NLRP3–IL‐1β–dependent inflammatory cascade. IL‐1β signals through IL‐1R1 on vlPAG/DRN VGLUT2+ neurons (vlPAG/DRNGlu), inducing hyperexcitability and driving the vlPAG/DRNGlu→BNSTGABA circuit to produce the affective component of neuropathic pain ...
Jing Yang   +7 more
wiley   +1 more source

Did Unilateral Divorce Laws Raise Divorce Rates? A Reconciliation and New Results: Comment [PDF]

open access: yes
The seminal papers by Friedberg (1998) and Wolfers (2006) find a positive effect of the regulatory change in divorce laws on divorce rates. Their results are based on analytical weights to correct for heteroskedasticity (WLS).
Ryan C.R. van Lamoen, Martijn I. Dröes
core  

Dysregulation of the MACF1‐Rab14/KIF16B‐FGFR Vesicular Trafficking Axis Skews MSC Lineage Commitment in Glucocorticoid‐Induced Osteoporosis

open access: yesAdvanced Science, EarlyView.
Under normal conditions, MACF1 interacts with Rab14 and facilitates KIF16B‐mediated FGFR vesicle trafficking along microtubules to the plasma membrane, thereby supporting BMSC differentiation. In contrast, chronic GC exposure suppresses MACF1 expression, disrupting this transport and causing intracellular FGFR retention, which blunts osteogenic ...
Peihong Su   +14 more
wiley   +1 more source

Targeting CXCR2 in Nociceptive Sensory Neurons Offers Novel Therapeutic Potentials for Postoperative Pain

open access: yesAdvanced Science, EarlyView.
Tissue incision induces CXCL5 release, which activates neuronal CXCR2 on incision‐innervating sensory neurons. Neuronal CXCR2 couples with TRPA1 to drive mechanical pain and engages p38 MAPK signaling to upregulate TRPV1 and promote heat pain. Targeted Cxcr2 knockdown relieves incisional pain while preserving CXCR2‐dependent neutrophil responses ...
Yushuang Pan   +10 more
wiley   +1 more source

Divorce and the birth control pill [PDF]

open access: yes
This paper explores the role of the birth control pill on divorce. To identify its effect, we use a quasi experiment exploiting the differences in the language of the Comstock anti-obscenity statutes approved in the 1800s and early 1900s in the US ...
MARCÉN, MIRIAM
core  

Endothelial miR‐15a/16‐1 Regulation of SYNE1 Mediates Structural and Functional Recovery after Traumatic Brain Injury

open access: yesAdvanced Science, EarlyView.
Endothelial miR‐15a/16‐1 deletion promotes long‐term recovery after traumatic brain injury by restoring SYNE1 expression. Enhanced endothelial SYNE1 preserves vascular integrity, protects white and gray matter, and improves neurological function. The endothelial miR‐15a/16‐1–SYNE1 axis emerges as a key regulator of neurovascular repair and a potential ...
Shun Li   +17 more
wiley   +1 more source

Economics of marriage and divorce [PDF]

open access: yes
In order to understand these ideas, we have to develop a model of both marriage and divorce (or, in other words, a model that allows for changes over time in the utility from marriage).
Leora Friedberg, Steven Stern
core  

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