Objective Our goal was to examine whether pre‐diagnostic plasma carotenoids and tocopherols are associated with amyotrophic lateral sclerosis (ALS). Methods A nested case–control study within 4 United States cohorts, where 154 participants with pre‐diagnostic blood‐draw, were diagnosed during follow‐up with amyotrophic lateral sclerosis (ALS). Controls
Éilis J. O'Reilly +7 more
wiley +1 more source
Diffusion MRI and α‐Synuclein Seed Amplification Status in Parkinson's Disease
Objective Positive α‐synuclein seed amplification assay (SAA) is a biomarker found in most people with Parkinson's disease (PD). We explored if free‐water (FW) imaging detects microstructural differences in the brains of patients with early PD with SAA+ or SAA– status.
Shannon Y. Chiu +145 more
wiley +1 more source
Combining EEG signals from the 2 members of a team to improve event identification. [PDF]
Fincham JM, Betts S, Anderson JR.
europepmc +1 more source
Genetic‐Proteomic Integration Identifies Predictive Plasma Proteins for Multiple Sclerosis
Objective Multiple sclerosis (MS) develops after a prolonged preclinical phase. Identifying circulating biomarkers that capture this early biology can improve risk stratification and guide intervention. We aimed to identify plasma proteins driving MS susceptibility using large‐scale proteogenomic integration and to evaluate their prediagnostic ...
Yuan Ding +5 more
wiley +1 more source
Toward Chromoselective Transformations in Biological Systems: Perspectives and Challenges
Controlling biological systems with small‐molecule chromophores has evolved into a powerful strategy and is applied from chemical biology to medicine. However, the complexity of in vivo systems cannot be matched by a single wavelength of light. Developing methods to combine and individually control multiple chromophores is crucial.
Nadja A. Simeth
wiley +1 more source
Medicaid Disenrollment Among Young Adults With and Without Complex Medical Conditions.
Cliff BQ +5 more
europepmc +1 more source
The role of professional networks and institutional prestige in shaping the first career moves of scholars. [PDF]
Rottenkolber A +6 more
europepmc +1 more source
A Generalization of the DMC. [PDF]
Tridenski S, Somekh-Baruch A.
europepmc +1 more source
Probabilistic mapping of lymph node metastasis in epithelial ovarian cancer: a retrospective cohort study using Bayesian network analysis. [PDF]
Xu H +11 more
europepmc +1 more source
A Sequential Design for Extreme Quantile Estimation Under Binary Sampling. [PDF]
Broniatowski M, Miranda E.
europepmc +1 more source

