Results 141 to 150 of about 9,325,572 (289)
Advanced Science, EarlyView.The protein aggregates and gene expression in the middle temporal gyrus (MTG) and somatosensory cortex (SOM) of the postmortem brains of 13 Alzheimer's disease patients were studied in detail, revealing that small hyperphosphorylated tau aggregates increase with Braak stage driven by microglial inflammation.
Elizabeth A. English +9 more
wiley +1 more source
Advanced Science, EarlyView.Temozolomide treatment activates GSK3β, driving DNMT1 phosphorylation, destabilization, and CD47 promoter hypomethylation in glioblastoma. This epigenetic shift upregulates CD47, enabling TMZ‐treated GBM cells to evade macrophage phagocytosis, survive chemotherapy, and acquire resistance.
Jie Li +11 more
wiley +1 more source
Predicting human microbe-drug associations via graph convolutional network with conditional random field. [PDF]
Bioinformatics, 2020 Long Y, Wu M, Kwoh CK, Luo J, Li X.
europepmc +1 more source
S-estimation and a robust conditional Akaike information criterion for linear mixed models. [PDF]
We study estimation and model selection on both the fixed and the random effects in the setting of linear mixed models using outlier robust S-estimators.
Tharmaratnam, Kukatharmini +1 more
core
Quantifying Uncertainties on Excursion Sets Under a Gaussian Random Field Prior
, 2016 We focus on the problem of estimating and quantifying uncertainties on the excursion set of a function under a limited evaluation budget. We adopt a Bayesian approach where the objective function is assumed to be a realization of a Gaussian random field.
Chevalier, Clément +3 more
core +1 more source
Advanced Science, EarlyView.D4F‐functionalized ceria nanozyme–CasRx nanoparticles preferentially target renal macrophages through SR‐B1‐mediated uptake in ischemia–reperfusion injury. Ceria scavenges excessive ROS, while CasRx silences STING signaling, shifting macrophages toward a less inflammatory, pro‐resolving state and increasing the proportion of regulatory T cells.
Weibo Chen +11 more
wiley +1 more source
Automatic facial expression recognition in an image sequence using conditional random field
, 2022 Facial expression recognition is one of the fields that nowadays has attracted the attention of many researchers. It is possible to automate facial expression recognition using artificial intelligence methods.
Roohallah Alizadehsani (13057710) +6 more
core
Advanced Science, EarlyView.This study identifies ALYREF as an oncogenic m5C reader in endometrial cancer. ALYREF recognizes NSUN2‐mediated m5C modification on XRCC6 mRNA to enhance transcript stability and increase XRCC6 expression. Elevated XRCC6 activates Wnt/β‐catenin signaling, resulting in accelerated tumor cell proliferation, migration, invasion, and xenograft tumor growth.
Linlin Hao +8 more
wiley +1 more source
Bayesian Conditional Random Fields
, 2005 We propose Bayesian Conditional Random Fields (BCRFs) for classifying interdependent and structured data, such as sequences, images or webs. BCRFs are a Bayesian approach to training and inference with conditional random fields, which were previously ...
Thomas P. Minka +2 more
core
Probabilistic Computing via Gate‐Tunable Random Telegraph Noise
Advanced Science, EarlyView.Intrinsic random telegraph noise in metal–oxide–semiconductor field‐effect transistors is harnessed to create gate‐tunable probabilistic bits. By modulating carrier‐trapping dynamics, the device produces stochastic binary outputs with a continuous bias‐to‐probability transfer.
Gyungwon Yun +8 more
wiley +1 more source