Results 151 to 160 of about 9,325,572 (289)
Advanced Science, EarlyView.Sepsis triggers hippocampal SIRT7 loss, promoting histone H2B succinylation and activation of the PD‐1/PD‐L1–PINK1 axis. This metabolic‐epigenetic cascade drives aberrant mitophagy and neuronal injury, ultimately causing cognitive deficits. Targeting SIRT7‐dependent succinylation offers a potential strategy to protect brain function during sepsis ...
Na Meng +12 more
wiley +1 more source
THEORY OF CONDITIONAL RANDOM FIELDS AND ITS ENGINEERING APPLICATION
, 1993 This paper outlines the theory of conditional random fields and its application.Probabilistic relations of conditional random fields are analytically developed; that is conditional means, first passage solution of conditional random fields, and method of
盛川, 仁, 亀田, 弘行
core
Advanced Science, EarlyView.The WTP is a key component of static drainage PEMFCs, enabling cathode water removal and gas sealing through capillary forces. This work investigates the mechanisms governing WTP drainage and sealing performance and develops predictive approaches for WTP design optimization.
Mengdi Guo +3 more
wiley +1 more source
Nonparametric Tests of Conditional Treatment Effects [PDF]
We develop a general class of nonparametric tests for treatment effects conditional on covariates. We consider a wide spectrum of null and alternative hypotheses regarding conditional treatment effects, including (i) the null hypothesis of the ...
Sokbae Lee, Yoon-Jae Whang
core
Interleukin‐39 is a Prognostic Biomarker and Therapy Target for Sepsis
Advanced Science, EarlyView.Sepsis triggers a significant increase in IL‐39 production, with circulating levels markedly elevated and positively correlated with disease severity and poor clinical prognosis in sepsis patients. Mechanistically, macrophage‐derived IL‐39 activates the GP130 signaling pathway via a ligand‐receptor interaction, thereby fueling the pro‐inflammatory ...
Feng‐zhi Zhang +9 more
wiley +1 more source
Inland Lakes Mapping for Monitoring Water Quality Using a Detail/Smoothing-Balanced Conditional Random Field Based on Landsat-8/Levels Data. [PDF]
Sensors (Basel), 2020 Wei L +7 more
europepmc +1 more source
Advanced Science, EarlyView.Biomineralization underpins skeletal development, yet its molecular control remains incompletely understood. Using a novel murine knockout model, this study reveals the essential and complementary roles of PHOSPHO1 and TNAP in postnatal skeletal development.
Lucie E. Bourne +15 more
wiley +1 more source
CONDITIONAL SIMULATION OF SPATIOTEMPORAL RANDOM FIELDS OF ENVIRONMENTAL CONTAMINATION
TASK Quarterly, 2006 The paper considers a method of conditional simulation of spatiotemporal scalar random fields of certain environmental phenomena. The method can be used to predict field values at given space points at specified time, on the basis of field values at ...
ROBERT JANKOWSKI, HENRYK WALUKIEWICZ
doaj
Mapping Embryonic Mouse Lung Development Using Enhanced Spatial Transcriptomics
Advanced Science, EarlyView.The mammalian lung contains ∼50 cell types arranged along the airway epithelium. Here, deterministic barcoding sequencing (DBiT‐seq) is optimized to nearly double transcript recovery, enabling highly sensitive spatial mapping of the embryonic mouse lung.
Pengfei Zhang +5 more
wiley +1 more source