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Revisiting Target‐Aware de novo Molecular Generation with TarPass: Between Rational Design and Texas Sharpshooter

open access: yesAdvanced Science, EarlyView.
TarPass provides a rigorous benchmark for target‐aware de novo molecular generation by jointly evaluating protein‐ligand interactions, molecular plausibility, and drug‐likeness on 18 well‐studied targets. Results show that current models often fail to consistently surpass random baseline in target‐specific enrichment, while post hoc multi‐tier virtual ...
Rui Qin   +11 more
wiley   +1 more source

VLibrasBD: A Brazilian Portuguese-Brazilian sign language (Libras) bilingual text dataset designed to support neural machine translation. [PDF]

open access: yesData Brief
Lima MA   +7 more
europepmc   +1 more source
Some of the next articles are maybe not open access.

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Conditionals and conditional thinking

Mind & Society, 2007
In this paper, we claim that the problem of conditionals should be dealt with by carefully distinguishing between thinking conditional propositions and conditional thinking, i.e. thinking on the basis of some supposition. This distinction deserves further investigation, if we are to make sense of some old and new experimental data concerning the ...
MANFRINATI A.   +2 more
openaire   +5 more sources

Conditional Association

Neural Computation, 2012
Estimating conditional dependence between two random variables given the knowledge of a third random variable is essential in neuroscientific applications to understand the causal architecture of a distributed network. However, existing methods of assessing conditional dependence, such as the conditional mutual information, are computationally ...
Seth, Sohan, Príncipe, José C.
openaire   +3 more sources

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