Effectiveness of regenerative medicine for skin lightening and rejuvenation: a systematic review of extracellular vesicles and conditioned media [PDF]
Stem Cell Research & TherapyAims and objectives This study aims to evaluate and summarize the efficacy and safety of extracellular vesicles (EVs) and conditioned media (CM) as emerging therapeutic approaches in regenerative medicine for skin rejuvenation and lightening.
Alireza Jafarzadeh +4 more
doaj +2 more sources
Ovarian Stromal Cell-Conditioned Media, but Not Co-Culture, Improves Survival in Feline Follicles [PDF]
AnimalsOvarian stromal cells play roles in in vivo folliculogenesis; however, little is known about their effect on in vitro cultured follicles. This study investigated the impact of ovarian stromal cell co-culture or conditioned medium (CM) on the survival and
Batsheva Marks +3 more
doaj +2 more sources
Physicochemical and Biological Modifications in Mesenchymal Stem Cells-Derived Conditioned Media Under Hypoxic Preconditioning: Impact on Oxidative Stress and Nanoparticle Stability [PDF]
LifeHypoxic preconditioning (HP) is a promising approach to enhance the therapeutic efficacy of mesenchymal stem cells (MSCs) by modulating their oxidative stress response, metabolic activity, and secretome composition.
Gülsemin Çiçek +4 more
doaj +2 more sources
Effect of Concentrated Fibroblast-Conditioned Media on In Vitro Maintenance of Rat Primary Hepatocyte. [PDF]
PLoS ONE, 2016 The effects of concentrated fibroblast-conditioned media were tested to determine whether hepatocyte function can be maintained without direct contact between hepatocytes and fibroblasts.
Dayeong Jeong +7 more
doaj +4 more sources
Amphiregulin-EGFR Signaling Mediates the Migration of Bone Marrow Mesenchymal Progenitors toward PTH-Stimulated Osteoblasts and Osteocytes [PDF]
, 2012 Intermittent administration of parathyroid hormone (PTH) dramatically increases bone mass and currently is one of the most effective treatments for osteoporosis. However, the detailed mechanisms are still largely unknown.
Chandra, Abhishek +6 more
core +13 more sources
Cells, 2022 Hepatocyte senescence is associated with liver fibrosis. However, the possibility of a direct, causal relation between hepatocyte senescence and hepatic stellate cell (HSC) activation was the subject of this study. Liver biopsy specimens obtained from 50
Pramudi Wijayasiri +6 more
doaj +1 more source
Journal of Functional Biomaterials, 2023 Titanium surface modifications are widely used to modulate cellular behavior by recognition of topographical cues. However, how those modifications affect the expression of mediators that will influence neighboring cells is still elusive.
Jorge Felipe Lima Teixeira +6 more
doaj +1 more source
Potential anti-ageing effects of probiotic-derived conditioned media on human skin cells
Acta Pharmaceutica, 2022 In this study, the protective functions of bacteria-free conditioned media from Bifidobacterium and Lactobacillus species against ultraviolet radiation-induced skin ageing and associated cellular damage were investigated.
Hong Yoo Kyung +8 more
doaj +1 more source
PLoS ONE, 2020 The pathogenesis of esophageal injury in gastroesophageal reflux disease (GERD) is incompletely understood. We modeled exposure of human esophageal myofibroblasts (HEMFs) to gastroesophageal reflux by repeated treatment with pH 4.5 and pH 4.5 bile salts ...
Liping Hu +5 more
doaj +3 more sources
Muscle metabolic stress determines cancer cachexia severity in mice
Frontiers in Physiology, 2022 Objectives: To determine the metabolic effects of cancer-conditioned media on myotube metabolism and to understand whether the variability of these effects is associated with cancer cachexia progression.Materials and methods: We established single-cell ...
Christiano Alves +3 more
doaj +1 more source