Results 11 to 20 of about 7,482,658 (287)

Conditioned Media from Human Pulp Stem Cell Cultures Improve Bone Regeneration in Rat Calvarial Critical-Size Defects

Journal of Functional Biomaterials, 2023
The aim of this study was to test whether lyophilized conditioned media from human dental pulp mesenchymal stem cell cultures promote the healing of critical-size defects created in the calvaria of rats.
Leonardo Fernandes Buss, Gustavo Sigrist de Martin, Elizabeth Ferreira Martinez, Isabela Amanda de Abreu Araújo Porcaro Filgueiras, José Luiz Magnabosco, Bruno Frenhan Alves, Bruno de Macedo Almeida, Tatiana Kotaka, Marcelo Lucchesi Teixeira, José Ricardo Muniz Ferreira, Daniel Navarro da Rocha, Raul Canal, Antonio Carlos Aloise, Lexie Shannon Holliday, André Antonio Pelegrine   +14 more
doaj   +2 more sources

Conditioned media from human osteoarthritic synovium induces inflammation in a synoviocyte cell line

Connective Tissue Research, 2019
Aim: Osteoarthritis (OA) is a whole joint pathology involving cartilage, synovial membrane, meniscus, subchondral bone, and infrapatellar fat pad (IFP). Synovitis has been widely documented in OA suggesting its important role in pathogenesis.
Elisa Belluzzi, Eleonora Olivotto, Assunta Pozzuoli   +2 more
exaly   +2 more sources

Calcium mimics the chemotactic effect of conditioned media and is an effective inducer of bone regeneration.

PLoS ONE, 2019
BackgroundAfter bone resorption, ions and degraded organic components are co-released into the extracellular space. Ions and growth factors, although different in their biological nature, induce a common and coordinated chemotactic effect.
Rubén Aquino-Martínez, David G Monroe, Francesc Ventura   +2 more
doaj   +2 more sources

Antimicrobial Activity of Soil Clostridium Enriched Conditioned Media Against Bacillus mycoides, Bacillus cereus, and Pseudomonas aeruginosa

Frontiers in Microbiology, 2020
The rise of antimicrobial resistant bacteria has fast-tracked the exploration for novel antimicrobial compounds. Reports on antimicrobial producing soil anaerobes such as Clostridium spp. are very limited. In the present study, the antimicrobial activity
Amila Srilal Nawarathna Weligala Pahalagedara, Amila Srilal Nawarathna Weligala Pahalagedara, Steve Flint, Jon Palmer, Arvind Subbaraj, Gale Brightwell, Tanushree Barua Gupta   +6 more
doaj   +2 more sources

Conditioned media derived from mesenchymal stem cell cultures: The next generation for regenerative medicine

Journal of Tissue Engineering and Regenerative Medicine, 2019
Recent studies suggest that the main driving force behind the therapeutic activity observed in mesenchymal stem cells (MSCs) are the paracrine factors secreted by these cells.
Tarini N A Gunawardena, Noor Hayaty Abu Kasim   +1 more
exaly   +2 more sources

Mesenchymal stem cells and conditioned media in the treatment of multiple sclerosis patients: Clinical, ophthalmological and radiological assessments of safety and efficacy

CNS Neuroscience and Therapeutics, 2017
This open‐label prospective phase I/IIa clinical study used autologous bone marrow‐derived mesenchymal stromal cells (BM‐MSCs) followed by mesenchymal stromal cells conditioned media (MSC‐CM) for the first time to treat multiple sclerosis (MS) patients ...
Said S Dahbour, Fatima Jamali, Ali Al-Radaideh   +2 more
exaly   +2 more sources

Functionalizing Collagen Membranes with MSC-Conditioned Media Promotes Guided Bone Regeneration in Rat Calvarial Defects

Cells, 2023
Functionalizing biomaterials with conditioned media (CM) from mesenchymal stromal cells (MSC) is a promising strategy for enhancing the outcomes of guided bone regeneration (GBR).
Siddharth Shanbhag, Carina Kampleitner, Niyaz Al-Sharabi, Samih Mohamed-Ahmed, Karol Ali Apaza Alccayhuaman, Patrick Heimel, Stefan Tangl, Andreas Beinlich, Neha Rana, Mariano Sanz, Einar K. Kristoffersen, Kamal Mustafa, Reinhard Gruber   +12 more
doaj   +3 more sources

Conditioned media from human umbilical cord blood-derived mesenchymal stem cells stimulate rejuvenation function in human skin

Biochemistry and Biophysics Reports, 2018
Developing treatments that inhibit skin aging is an important research project. Rejuvenation, which focuses on prevention of skin aging, is one of the major issues. Recent studies suggested that mesenchymal stem cells (MSCs) secrete many cytokines, which
Kwang-Won Seo, Kyung-Sun Kang
exaly   +2 more sources

Current status of the applications of conditioned media derived from mesenchymal stem cells for regenerative medicine.

Physiological Research, 2023
Recently published studies suggest that the paracrine substances released by mesenchymal stem cells (MSCs) are the primary motive behind the therapeutic action reported in these cells.
V. Smolinska, M. Boháč, L. Danišovič
semanticscholar   +1 more source

MSCs’ conditioned media cytokine and growth factor profiles and their impact on macrophage polarization

Stem cell research & therapeutics, 2023
Background There is a growing body of evidence that multipotent mesenchymal stromal cells’ (MSCs’) remarkable therapeutic potential is attributed not only to their differentiation and regenerative capacity, but also to the paracrine effect, underlying ...
M. Peshkova, A. Korneev, S. Suleimanov, I. I. Vlasova, A. Svistunov, N. Kosheleva, P. Timashev   +6 more
semanticscholar   +1 more source