Results 21 to 30 of about 7,482,658 (287)

Anti-inflammatory effects of mesenchymal stem cell-conditioned media inhibited macrophages activation in vitro

open access: yesScientific Reports, 2022
The immunomodulatory effects of mesenchymal stem cells (MSCs) on macrophages have been reported, however, the underlying mechanism remains unknown. Therefore, this study aimed to investigate the anti-inflammatory effects of MSCs on lipopolysaccharide ...
Q. Jin   +4 more
semanticscholar   +1 more source

Identification of secreted proteins by comparison of protein abundance in conditioned media and cell lysates

open access: yesbioRxiv, 2022
Analysis of the full spectrum of secreted proteins in cell culture is complicated by leakage of intracellular proteins from damaged cells. To address this issue, we compared the abundance of individual proteins between the cell lysate and the conditioned
Prabhodh S. Abbineni   +6 more
semanticscholar   +1 more source

Selectivity of direct plasma treatment and plasma-conditioned media in bone cancer cell lines

open access: yesScientific Reports, 2021
Atmospheric pressure plasma jets have been shown to impact several cancer cell lines, both in vitro and in vivo. These effects are based on the biochemistry of the reactive oxygen and nitrogen species generated by plasmas in physiological liquids ...
I. Hamouda   +4 more
semanticscholar   +1 more source

The culture microenvironment of juvenile idiopathic arthritis synovial fibroblasts is favorable for endochondral bone formation through BMP4 and repressed by chondrocytes

open access: yesPediatric Rheumatology Online Journal, 2021
Background We examined influences of conditioned media from chondrocytes (Ch) on juvenile idiopathic arthritis synovial fibroblasts (JFLS) and potential for JFLS to undergo endochondral bone formation (EBF).
Megan M. Simonds   +5 more
doaj   +1 more source

Site-specific keloid fibroblasts alter the behaviour of normal skin and normal scar fibroblasts through paracrine signalling. [PDF]

open access: yesPLoS ONE, 2013
Keloid disease (KD) is an abnormal cutaneous fibroproliferative disorder of unknown aetiopathogenesis. Keloid fibroblasts (KF) are implicated as mediators of elevated extracellular matrix deposition.
Kevin J Ashcroft   +2 more
doaj   +1 more source

Human Lung Mast Cells Impair Corticosteroid Responsiveness in Human Airway Smooth Muscle Cells

open access: yesFrontiers in Allergy, 2021
The mechanisms underlying corticosteroid insensitivity in severe asthma have not been elucidated although some indirect clinical evidence points toward a role of mast cells.
Abdulrahman Alzahrani   +10 more
doaj   +1 more source

Reactive oxygen species and nitric oxide signaling in bystander cells. [PDF]

open access: yesPLoS ONE, 2018
It is now well accepted that radiation induced bystander effects can occur in cells exposed to media from irradiated cells. The aim of this study was to follow the bystander cells in real time following addition of media from irradiated cells and to ...
Kishore Kumar Jella   +4 more
doaj   +1 more source

Pancreatic cancer-associated diabetes mellitus: an open field for proteomic applications. [PDF]

open access: yes, 2005
Background: Diabetes mellitus is associated with pancreatic cancer in more than 80% of the cases. Clinical, epidemiological, and experimental data indicate that pancreatic cancer causes diabetes mellitus by releasing soluble mediators which interfere ...
BALDO G   +11 more
core   +1 more source

Protective effect of stromal Dickkopf-3 in prostate cancer: opposing roles for TGFBI and ECM-1 [PDF]

open access: yes, 2018
Aberrant transforming growth factor–β (TGF-β) signaling is a hallmark of the stromal microenvironment in cancer. Dickkopf-3 (Dkk-3), shown to inhibit TGF-β signaling, is downregulated in prostate cancer and upregulated in the stroma in benign prostatic ...
A Dutta   +65 more
core   +2 more sources

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