Results 71 to 80 of about 7,482,658 (287)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Effect of Multiple-Cycle Collections of Conditioned Media from Different Cell Sources towards Fibroblasts in In Vitro Wound Healing Model

Pharmaceutics
Conditioned media refers to a collection of the used cell culture media. The goal of this study was to evaluate the possible impacts of different conditioned media collected across a number of cycles on the fibroblast proliferation, migration, and ...
Nur Izzah Md Fadilah, Mh Busra Fauzi, Manira Maarof   +2 more
doaj   +1 more source

The “StemDif Sensor Test”: A Straightforward, Non-Invasive Assay to Characterize the Secreted Stemness and/or Differentiation Activities of Tumor-Derived Cancer Cell Lines

Biomedicines, 2023
Cancer stem cells are a subpopulation of tumor cells characterized by their ability to self-renew, induce tumors upon engraftment in animals and exhibit strong resistance to chemotherapy and radiotherapy.
Aya Abou Hammoud, Julie Giraud, Xavier Gauthereau, Camille Blanchard, Sophie Daburon, Marco Zese, Silvia Molina-Castro, Pierre Dubus, Christine Varon, Helene Boeuf   +9 more
doaj   +1 more source

Induction of epithelial to mesenchymal transition in PMC42-LA human breast carcinoma cells by carcinoma-associated fibroblast secreted factors [PDF]

, 2007
Background\ud \ud Breast carcinoma is accompanied by changes in the acellular and cellular components of the microenvironment, the latter typified by a switch from fibroblasts to myofibroblasts.
Stephanie C Lebret, Donald F Newgreen, Erik W Thompson, M Leigh Ackland, A Noel, HF Dvorak, C Gache, MH Barcellos-Hoff, E Farber, MH Barcellos-Hoff, MJ Bissell, TD Tlsty, MH Barcellos-Hoff, NA Bhowmick, AF Olumi, SW Hayward, D Lazard, G Gabbiani, O De Wever, SC Heffelfinger, KJ Cullen, E Matsumoto, SH Barsky, SB Deak, O Brummer, BS Nielsen, RH Whitehead, RH Whitehead, ML Ackland, ML Ackland, SC Lebret, RH Whitehead, KM Darcy, S Welt, MJ Scanlan, WJ Rettig, P Garin-Chesa, L Ronnov-Jessen, H Chen, UH Frixen, J Luo, G Berx, SA Rasbridge, DI Bellovin, H Kuroda, E Tucker, S Orsulic, JF Yang, JP Thiery, EW Thompson, CL Sommers, CL Sommers, M Osborn, E Fuchs, SD Bernal, W Xian, OW Petersen, ML Stracke, LA Liotta, Y Li, C Gilles, S Bellusci, S Bellusci, H Mukaida, D Brouty-Boye, L Adam, LJ Hofland, MF Lefebvre, DJA Orr, J Liu, J Enami, EF Adams, KE van Roozendaal, D Brouty-Boye, A Sadlonova, M Yashiro   +75 more
core   +2 more sources

Conditioned media from dental pulp stem cells improved diabetic polyneuropathy through anti‐inflammatory, neuroprotective and angiogenic actions: Cell‐free regenerative medicine for diabetic polyneuropathy

Journal of Diabetes Investigation, 2019
Dental pulp stem cells (DPSCs) can be easily obtained from teeth for general orthodontic reasons. We have previously reported the therapeutic effects of DPSC transplantation for diabetic polyneuropathy. As abundant secretomes from DPSCs are considered to
Eriko Makino, N. Nakamura, Megumi Miyabe, Mizuho Ito, Saki Kanada, Masaki Hata, Tomokazu Saiki, K. Sango, H. Kamiya, J. Nakamura, K. Miyazawa, S. Goto, T. Matsubara, K. Naruse   +13 more
semanticscholar   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Lorenzo Milani in our times [PDF]

, 2013
This article pays tribute to one of Europe's foremost critical pedagogues, the Tuscan Don Lorenzo Milani, on the ninetieth anniversary of his birth. It highlights the key moments in his life as priest and educator as well as his pedagogical approach ...
Mayo, Peter
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

The Role of Trophoblastic Stem Cells Conditioned Media on JAR Cell Culture

Proceedings, 2017
Trophoblasts are placenta-specific epithelial cells which play an important role in embryo implantation. Trophoblast stem cells (TSCs) are precursor cells of placenta and can be derived before or after implantation. During TSCs culture, several molecules
Hilal Kabadayı, Remziye Kendirci, H. Seda Vatansever   +2 more
doaj   +1 more source

Imagined Hierarchies as Conditionals of Gender in Aesthetics [PDF]

, 2016
The attributes of gender in the media are disputable. This can be explained by a conflict generated by culturally acquired alternative imagined hierarchies which are not compatible or may be even contradictory.
Mróz, Adrian
core   +1 more source