Results 201 to 210 of about 5,357,439 (379)

What drives seasonal fluctuations of body condition in a semelparous income breeder octopus?

, 2011
Antoni Quetglas, Francesc Ordines, María Valls   +2 more
openalex   +2 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

A Pilot Study for "In Vitro" Testing the Surface Conditioning Effects on CAD/CAM Hybrid Nanoceramic Adhesion. [PDF]

Dent J (Basel)
Iliev GV, Ciocan LT, Vasilescu VG, Vărzaru G, Miculescu F, Țâncu AMC, Imre M, Pițuru SM.   +7 more
europepmc   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Low-dimensional signatures of neuronal activity associated with long-term operant conditioning in Aplysia. [PDF]

Commun Biol
Vanaki S, Gonzalez NO, Neveu CL, Momohara Y, Aazhang B, Byrne JH.   +5 more
europepmc   +1 more source

Environmental condition alters amphetamine self-administration: role of the MGluR5 receptor and schedule of reinforcement

, 2015
David L. Arndt, K. C. Johns, Z. K Dietz, Mary E. Cain   +3 more
openalex   +2 more sources

The Twin Condition and the Couple Effects on Personality Development [PDF]

, 1976
René Zazzo
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Serotonergic-dependent awareness is required for trace conditioning in honeybees. [PDF]

iScience
Macri C, Paoli M, Alamia A, Gho M, Isabel G, Giurfa M.   +5 more
europepmc   +1 more source

On a boundedness condition for operators with a singleton spectrum [PDF]

, 1980
J. P. Williams
openalex   +1 more source