Results 41 to 50 of about 895,919 (342)

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

FEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali, Gloria Giacomello, Michela Vuono, Silvia Gregori   +3 more
wiley   +1 more source

Conditioning Perspectives for Primary Immunodeficiency Stem Cell Transplants

Frontiers in Pediatrics, 2019
The majority of children undergoing Hematopoietic Stem cell Transplantation (HSCT) require conditioning therapy to make space and prevent rejection of the donor stem cells.
Peter Shaw, Judith Shizuru, Manfred Hoenig, Paul Veys, IEWP-EBMT   +4 more
doaj   +1 more source

Physical Preparation in Female Rugby Codes: An Investigation of Current Practices

Frontiers in Sports and Active Living, 2020
Female sports have recently seen a dramatic rise in participation and professionalism world-wide. Despite progress, the infrastructure and general sport science provisions in many female sports are behind their male counterparts.
Omar Heyward, Omar Heyward, Ben Nicholson, Stacey Emmonds, Stacey Emmonds, Gregory Roe, Gregory Roe, Ben Jones, Ben Jones, Ben Jones, Ben Jones, Ben Jones   +11 more
doaj   +1 more source

Addition of Rituximab in Reduced Intensity Conditioning Regimens for B-Cell Malignancies Does Not Influence Transplant Outcomes: EBMT Registry Analyses Following Allogeneic Stem Cell Transplantation for B-Cell Malignancies

Frontiers in Immunology, 2021
Rituximab (R) is increasingly incorporated in reduced intensity conditioning (RIC) regimens for allogeneic hematopoietic cell transplantation (alloHCT) in patients with B-cell malignancies, not only to improve disease control, but also to prevent graft ...
Agnieszka Tomaszewska, Madan Jagasia, Eric Beohou, Steffie van der Werf, Didier Blaise, Edward Kanfer, Noel Milpied, Péter Reményi, Fabio Ciceri, Jean H. Bourhis, Patrice Chevallier, Carlos Solano, Gerard Socié, Benedetto Bruno, Alessandro Rambaldi, Luca Castagna, Nicolaus Kröger, Paolo Corradini, Boris Afanasyev, Marco Ladetto, Dietger Niederwieser, Christof Scheid, Henrik Sengeloev, Frank Kroschinsky, Ibrahim Yakoub-Agha, Helene Schoemans, Christian Koenecke, Olaf Penack, Zinaida Perić, Hildegard Greinix, Rafael F. Duarte, Grzegorz W. Basak   +31 more
doaj   +1 more source

To condition or not to condition—That is the question: The evolution of nonmyeloablative conditions for transplantation [PDF]

Experimental Hematology, 2016
In 1985, Eugene Cronkite and his colleagues published, in Experimental Hematology, data indicating that five consecutive "transfusions" of large numbers of marrow cells significantly increase the number of donor-derived cells detected by day 10 of a spleen colony-forming assay, the most primitive hematopoietic cells detectable at that time, present in ...
openaire   +3 more sources

On conditional decomposability [PDF]

Systems & Control Letters, 2012
The requirement of a language to be conditionally decomposable is imposed on a specification language in the coordination supervisory control framework of discrete-event systems. In this paper, we present a polynomial-time algorithm for the verification whether a language is conditionally decomposable with respect to given alphabets.
Komenda, J. (Jan), Masopust, T. (Tomáš), van Schuppen, J. H.   +2 more
openaire   +3 more sources

FoxO1 signaling in B cell malignancies and its therapeutic targeting

FEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac, Petra Pavelkova, Laura Ondrisova, Marek Mraz   +3 more
wiley   +1 more source

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

FEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi, WanTing Kong, Camille Blériot, Joel T. Haas   +3 more
wiley   +1 more source

The effect of stroboscopic vision training on the performance of elite curling athletes

Scientific Reports
The aim of the study was to investigate the impacts of four weeks of stroboscopic vision training (SVT) and four weeks of temporal feedback training (TFT) on elite curling athletes’ duration judgment, as well as stone delivery performance (delivery speed
Tianhe Li, Xiaoyao Wang, Zhiqiang Wu, Yapu Liang   +3 more
doaj   +1 more source

Characterization of NMDAR-independent learning in the hippocampus.

Frontiers in Behavioral Neuroscience, 2011
It is currently thought that memory formation requires the activation of NMDA receptors (NMDARs) in the hippocampus. However, recent studies indicate that these receptors are not necessary for all forms of learning. The current experiments examine this
Kaycie Kuss Tayler, Elizabeth eLowry, Kazumasa eTanaka, Brynne eLevy, Leon eReijmers, Mark eMayford, Brian J Wiltgen   +6 more
doaj   +1 more source