Results 61 to 70 of about 895,919 (342)

Functional variation among LPMOs revealed by the inhibitory effects of cyanide and buffer ions

FEBS Letters, EarlyView.
This study addresses the inhibition of lytic polysaccharide monooxygenases (LPMOs) by cyanide and explains how and why the magnitude of observed inhibitory effects depends on the way LPMO reactions are setup and on the type of LPMO. Enzymes known as lytic polysaccharide monooxygenases (LPMOs) are mono‐copper polysaccharide‐degrading peroxygenases that ...
Ole Golten, Lorenz Schwaiger, Zarah Forsberg, Kelsi R. Hall, Anton A. Stepnov, Tom Z. Emrich‐Mills, Iván Ayuso‐Fernández, Morten Sørlie, Roland Ludwig, Åsmund Kjendseth Røhr, Vincent G. H. Eijsink   +10 more
wiley   +1 more source

Hematopoietic Stem Cell Transplantation—50 Years of Evolution and Future Perspectives

Rambam Maimonides Medical Journal, 2014
Hematopoietic stem cell transplantation is a highly specialized and unique medical procedure. Autologous transplantation allows the administration of high-dose chemotherapy without prolonged bone marrow aplasia.
Israel Henig, Tsila Zuckerman
doaj   +1 more source

Ablation of LRP6 in alpha‐smooth muscle actin‐expressing cells abrogates lung inflammation and fibrosis upon bleomycin‐induced lung injury

FEBS Letters, EarlyView.
Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung, Mikhail G. Dozmorov, SuJeong Song, Theingi Aung, Min Hee Park, Patricia J. Sime, Wook‐Jin Chae   +6 more
wiley   +1 more source

Differential conditioning of conditioned enhancement and positive conditioned suppression [PDF]

Bulletin of the Psychonomic Society, 1978
Rats, barpressing for sucrose solution, were divided into three groups, each of which was exposed to a different VI schedule. During each session, four long tone CSs and four short light CSs were followed by a food pellet for half of each group. For the other half, the long CS was a tone and the short CS was light.
Donald Meltzer, Robert J. Hamm
openaire   +2 more sources

Characteristics of the Kelch domain containing (KLHDC) subfamily and relationships with diseases

FEBS Letters, EarlyView.
The Kelch protein superfamily includes 63 members, with the KLHDC subfamily having 10 proteins. While their functions are not fully understood, recent advances in KLHDC2's structure and role in protein degradation have highlighted its potential for drug development, especially in PROTAC therapies.
Courtney Pilcher, Paula Armina V. Buco, Jia Q. Truong, Paul A. Ramsland, Monique F. Smeets, Carl R. Walkley, Jessica K. Holien   +6 more
wiley   +1 more source

Weighted conditional type operators between different Orlicz spaces [PDF]

arXiv, 2015
In this note we consider weighted conditional type operators between different Orlicz spaces and generalized conditional type Holder inequality that we defined in [2]. Then we give some necessary and sufficient conditions for boundedness of weighted conditional type operators.
arxiv  

Insertion of the FeB cofactor in cNORs lacking metal inserting chaperones

FEBS Letters, EarlyView.
Nitric oxide reductase is an enzyme found in the bacterial denitrification pathway. The NOR active site contains a non‐heme iron, often, but not always inserted with the assistance of chaperones. Here, we study the insertion of FeB in the subfamily of cNORs lacking chaperones and found a putative channel, conserved in the family, perhaps enabling the ...
Sofia Appelgren, Pia Ädelroth
wiley   +1 more source

Erythrocyte nicotinamide adenine dinucleotide concentration is enhanced by systematic sports participation

BMC Sports Science, Medicine and Rehabilitation
Background Nicotinamide adenine dinucleotide (NAD+), nicotinamide adenine dinucleotide phosphate (NADP+), and their reduced forms (NADH and NADPH) are the vital cofactors for most cellular oxidation/reduction reactions and therefore influence most ...
Barbara Pospieszna, Krzysztof Kusy, Ewa Maria Slominska, Jacek Zieliński, Monika Ciekot-Sołtysiak   +4 more
doaj   +1 more source

Influence du matériau sur l'évolution du vin conditionné en contenant de faible volume

OENO One, 1988
L'évolution du vin en bouteilles de 18,7 cl avec bouchon à vis est étudiée. On compare l'effet du matériau des bouteilles: verre, PET,PVC à 20° Cet 30° C sur la conservation des vins. Le PVC ne permet jamais une conservation correcte.
Jean-Noël Boidron, M. Bar
doaj   +1 more source

An aberration criterion for conditional models [PDF]

arXiv, 2019
Conditional models with one pair of conditional and conditioned factors in Mukerjee et al. (2017) are extended to two pairs in this paper. The extension includes the parametrization, effect hierarchy, sufficient conditions for universal optimality, aberration, complementary set theory and the strategy for finding minimum aberration designs.
arxiv