Results 131 to 140 of about 45,479 (218)

Population pharmacokinetics of levofloxacin in breastmilk in patients with rifampicin‐resistant tuberculosis

British Journal of Clinical Pharmacology, EarlyView.
Levofloxacin is a widely used antibiotic included in rifampicin‐resistant tuberculosis (RR‐TB) treatment. Data describing levofloxacin concentrations in breastmilk and infant exposure are limited. We analysed data from two South African studies of breastfeeding women receiving levofloxacin (750–1000 mg daily) for RR‐TB.
Sharon Sawe, Lufina Tsirizani, Buyisile Mkhize, Lubbe Wiesner, Gary Maartens, Francesca Conradie, Richard Court, Marian Loveday, Catriona Waitt, Paolo Denti   +9 more
wiley   +1 more source

HIV risks and vulnerabilities reported among adolescent girls and young women accessing DREAMS services in three Zambian districts: Monze, Mazabuka, and Mongu, 2020-2022. [PDF]

AIDS Res Ther
Tembo K, Baumhart C, Mwango L, Lindsay B, Olowski P, Chipukuma J, Olufunso A, Mujansi M, Kaliki B, Chituwo O, Muleya C, Mwila A, Claassen CW.   +12 more
europepmc   +1 more source

Low‐intervention clinical trials in Spain: Do they progress?

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Low‐Intervention Clinical Trials (LICTs) are generally pragmatic trials that investigate medicinal products already authorized for use. In 2014, simplified regulatory frameworks were introduced for LICTs with the aim of reducing regulatory burden and operational complexity, to foster non‐commercial clinical trials (NCCTs); the mandatory ...
Claudia Erika Delgado‐Espinoza, Mayro J. Cortés Pestana, Kristopher Amaro, Rosa M. Antonijoan, Caridad Pontes   +4 more
wiley   +1 more source

Improving HIV assisted partner services outcomes by eliciting additional partners after the initial encounter. [PDF]

PLOS Glob Public Health
Otieno G, Masyuko S, Roy Paladhi U, Kariithi E, Sharma M, Kingston H, Lagat H, Katz DA, Wamuti B, Macharia P, Bosire R, Mugambi M, Weiner BJ, Farquhar C.   +13 more
europepmc   +1 more source

Model‐informed precision dosing of carboplatin in cancer patients by leveraging myelosuppression data from electronic health records

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims This study aimed to develop and validate a population pharmacokinetic‐pharmacodynamic (pop‐PK‐PD) model to describe carboplatin‐induced myelosuppression in cancer patients and support dose individualization. Methods Data from 580 cancer patients treated with carboplatin at Amsterdam UMC between 2019 and 2022 were used for model ...
Alessandro De Carlo, Elena Maria Tosca, Mirjam Crul, Tim Schutte, Lia van Zuijlen, Idris Bahce, Medhat M. Said, Jan Buter, Harmen Huls, Paolo Magni, Imke Bartelink   +10 more
wiley   +1 more source

Predictive factors associated with sexual activity and consistent condom use during travel abroad: a cross-sectional survey of young Canadian adults. [PDF]

Reprod Health
Gareau E, Phillips KP.
europepmc   +1 more source

Pharmacokinetic modelling of intravenous immunoglobulin in children with primary immunodeficiencies and secondary antibody deficiencies

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Children with primary immunodeficiency (PID) and secondary antibody deficiency (SAD) often require immunoglobulin replacement therapy due to low plasma immunoglobulin G (IgG) levels and recurrent infections. Existing pharmacokinetic models for immunoglobulin in PID patients predominantly focus on adults, with limited attention to ...
Iek Leng Cheng, Zhong Hui Huang, Austen Worth, Claire Booth, Joseph F. Standing   +4 more
wiley   +1 more source

Effectiveness of social network site-based interventions promoting condom use among youth: A systematic review based on the intervention mapping taxonomy. [PDF]

Prev Med Rep
de Visser I, Gaetani M, Smith S, Verduyn P, Ten Hoor G, Zimmermann HML.   +5 more
europepmc   +1 more source

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

British Journal of Clinical Pharmacology, EarlyView.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale, Clare Guilding, Jennifer Koenig, Michael Okorie, Reecha Sofat, Simon Maxwell   +5 more
wiley   +1 more source

Safe Sex and the Debate over Condoms on Campus in the 1980s: Sperm Busters at Harvard and Protection Connection at the University of Texas at Austin. [PDF]

J Hist Med Allied Sci
Osseo-Asare AD.
europepmc   +1 more source